MRM1 and COQ8A

Data Source:
BioGRID (two hybrid)

		MRM1	COQ8A
Description		mitochondrial rRNA methyltransferase 1	coenzyme Q8A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	RNA Binding Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding
	Biological Process	RRNA 2'-O-methylation	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways		rRNA modification in the mitochondrion
Drugs			Fostamatinib
Diseases			Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)
Interacting Genes		43 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CGGBP1 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1	26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2
Entrez ID		79922	56997
HPRD ID		08656	07375
Ensembl ID		ENSG00000278619	ENSG00000163050
Uniprot IDs		Q6IN84	Q8NI60
PDB IDs			4PED 5I35
Enriched GO Terms of Interacting Partners?
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