MESD and COL10A1

Data Source:
BioGRID (two hybrid)

		MESD	COL10A1
Description		mesoderm development LRP chaperone	collagen type X alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Skeletal System Development Extracellular Matrix Organization
Pathways			Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen chain trimerization
Drugs
Diseases			Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
GWAS			Age-related macular degeneration ( 23455636 21665990) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		75 interacting genes: ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SIK1B SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	10 interacting genes: ANXA5 BANP CIDEB MESD NRF1 P4HB SGTB UBQLN1 UBQLN2 VSNL1
Entrez ID		23184	1300
HPRD ID		12129	00357
Ensembl ID		ENSG00000117899	ENSG00000123500
Uniprot IDs		Q14696	A0A650AXN9 Q03692
PDB IDs			1GR3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?