MESD and SNX7

Data Source:
BioGRID (two hybrid)

		MESD	SNX7
Description		mesoderm development LRP chaperone	sorting nexin 7
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Cytoplasmic Vesicle Membrane
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Protein Transport
Pathways
Drugs
Diseases
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Copper levels ( 26025379) Dental caries ( 23259602) Disease progression in age-related macular degeneration ( 29346644) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General risk tolerance (MTAG) ( 30643258) Insulin-related traits (multivariate analysis) ( 32002517) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Methadone dose in opioid dependence ( 28115739) Night sleep phenotypes ( 27126917) Proinsulin levels ( 21873549) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097 31123309)
Interacting Genes		75 interacting genes: ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SIK1B SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	10 interacting genes: ABI2 BIRC3 HGS HMOX2 MAGEA11 MESD POLR2L SNX4 TBC1D21 TEX11
Entrez ID		23184	51375
HPRD ID		12129	15416
Ensembl ID		ENSG00000117899	ENSG00000162627
Uniprot IDs		Q14696	B4DP69 E9PNL2 Q9UNH6
PDB IDs			3IQ2
Enriched GO Terms of Interacting Partners?
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