COL10A1 and VSNL1

Data Source:
BioGRID (two hybrid)

		COL10A1	VSNL1
Description		collagen type X alpha 1 chain	visinin like 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix	Cytosol Membrane
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding	Calcium Ion Binding Protein Binding
	Biological Process	Skeletal System Development Extracellular Matrix Organization	Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion
Pathways		Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen chain trimerization
Drugs
Diseases		Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
GWAS		Age-related macular degeneration ( 23455636 21665990) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Energy expenditure ( 30071075) Psychosis and Alzheimer's disease ( 22005930) Response to fenofibrate (total cholesterol levels) ( 27002377) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		10 interacting genes: ANXA5 BANP CIDEB MESD NRF1 P4HB SGTB UBQLN1 UBQLN2 VSNL1	17 interacting genes: ACTB ATXN1 C1QTNF2 CDSN CHRNA4 COL10A1 DTX2 ENDOD1 FAM131C GFI1B LITAF SPRED1 SPRED2 SPRY3 SRL TEX13B TFF1
Entrez ID		1300	7447
HPRD ID		00357	02890
Ensembl ID		ENSG00000123500	ENSG00000163032
Uniprot IDs		A0A650AXN9 Q03692	P62760
PDB IDs		1GR3
Enriched GO Terms of Interacting Partners?
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