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TMEM31 and DERL1
Data Source:
BioGRID
(two hybrid)
TMEM31
DERL1
Description
transmembrane protein 31
derlin 1
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Hrd1p Ubiquitin Ligase ERAD-L Complex
Early Endosome
Late Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1-VIMP Complex
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Molecular Function
Protein Binding
Protease Binding
Signal Recognition Particle Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Signaling Receptor Activity
MHC Class I Protein Binding
Identical Protein Binding
Protein-containing Complex Binding
ATPase Binding
Misfolded Protein Binding
Ubiquitin-specific Protease Binding
Biological Process
Protein Folding
Response To Unfolded Protein
Viral Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Endoplasmic Reticulum Unfolded Protein Response
Retrograde Protein Transport, ER To Cytosol
Positive Regulation Of Protein Ubiquitination
Protein Destabilization
Positive Regulation Of Protein Binding
ERAD Pathway
Establishment Of Protein Localization
Transmembrane Transport
ER-associated Misfolded Protein Catabolic Process
Pathways
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Defective CFTR causes cystic fibrosis
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Mean reticulocyte volume (
32888494
)
Metabolite levels (
23823483
)
Interacting Genes
141 interacting genes:
ABHD16A
ABHD5
AGPAT4
AGTRAP
ANKRD46
APOD
ARV1
ATP5MC3
ATP6V0C
BCAP31
BLCAP
BMP10
BNIP1
BTN2A2
C14orf180
C2CD2L
CAMLG
CCL4
CGRRF1
CLDND2
CLN5
CLRN1
CMTM7
CNIH3
COX14
COX20
CTSA
CTXN3
CXCL9
CXorf66
CYB561A3
CYB5R3
DEFB103A
DEFB103B
DEFB105A
DEFB105B
DERL1
DERL3
DGAT2L6
DHRSX
DNAJC30
EBP
EHHADH
EMP1
ERG28
FAXDC2
FCER1G
FKBP8
FXYD6
GIMAP5
GJB2
GJD4
GPR151
GUCA2A
GYPA
HERPUD2
HIGD1C
HSD17B13
HSD3B7
IFITM5
ITGAM
LHFPL5
LPAR3
LRAT
LY6D
MALL
MFSD14B
MMP14
MS4A1
NAT8
NINJ1
NINJ2
NSDHL
ORMDL2
OTOP3
OTULINL
PEDS1-UBE2V1
PLN
PLP1
PLP2
PMP22
PNLIPRP1
PTPN1
RDH11
REEP2
RETREG3
RNF144A
RNF19B
RTP2
SELENOK
SELENOM
SERP2
SGTA
SLC30A8
SLC35C2
SLC35E4
SLC39A6
SLC41A1
SLC66A2
SLC7A14
SMAGP
SMIM1
SMIM3
SMPD2
SNORC
SPTSSA
STX12
STX5
SYNGR1
TEX264
TIMMDC1
TMBIM6
TMEM107
TMEM121
TMEM14A
TMEM14C
TMEM182
TMEM203
TMEM208
TMEM218
TMEM239
TMEM242
TMEM254
TMEM255B
TMEM44
TMEM50A
TMEM86A
TMX2
TNFRSF10B
TRARG1
TSPAN2
TVP23B
UBE2J1
UBQLN1
UBQLN2
VAMP2
VAMP3
VAMP5
YIF1A
YIPF6
ZFPL1
33 interacting genes:
ABHD4
AMFR
APP
AQP6
CFTR
CIAO2A
FCRL4
FFAR2
GAD2
HLA-A
KASH5
LMNA
LNX1
MELTF
REEP4
RETREG3
RHO
SCN3B
SELENOS
SLC10A1
SLC10A6
SLC30A8
SLC7A14
SLC7A8
TCF25
TEX44
TMED8
TMEM31
TMX2
TRIM32
UBE2J1
UBXN6
VCP
Entrez ID
203562
79139
HPRD ID
06652
12302
Ensembl ID
ENSG00000179363
ENSG00000136986
Uniprot IDs
A0A140VK58
Q5JXX7
A0A024R9G3
E5RGY0
Q9BUN8
PDB IDs
5GLF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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