Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
DERL1 and RHO
Data Source:
BioGRID
(pull down)
DERL1
RHO
Description
derlin 1
rhodopsin
Image
GO Annotations
Cellular Component
Hrd1p Ubiquitin Ligase ERAD-L Complex
Early Endosome
Late Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1-VIMP Complex
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Golgi Membrane
Photoreceptor Outer Segment
Photoreceptor Inner Segment
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Integral Component Of Membrane
Golgi-associated Vesicle Membrane
Photoreceptor Outer Segment Membrane
Ciliary Membrane
Photoreceptor Inner Segment Membrane
Sperm Midpiece
Photoreceptor Disc Membrane
Sperm Head Plasma Membrane
Molecular Function
Protease Binding
Signal Recognition Particle Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Signaling Receptor Activity
MHC Class I Protein Binding
Identical Protein Binding
Protein-containing Complex Binding
ATPase Binding
Misfolded Protein Binding
Ubiquitin-specific Protease Binding
G Protein-coupled Receptor Activity
11-cis Retinal Binding
Protein Binding
G Protein-coupled Photoreceptor Activity
Metal Ion Binding
Biological Process
Protein Folding
Response To Unfolded Protein
Viral Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Endoplasmic Reticulum Unfolded Protein Response
Retrograde Protein Transport, ER To Cytosol
Positive Regulation Of Protein Ubiquitination
Protein Destabilization
Positive Regulation Of Protein Binding
ERAD Pathway
Establishment Of Protein Localization
Transmembrane Transport
ER-associated Misfolded Protein Catabolic Process
Retinoid Metabolic Process
Protein Phosphorylation
G Protein-coupled Receptor Signaling Pathway
Visual Perception
Phototransduction
Phototransduction, Visible Light
Absorption Of Visible Light
Rhodopsin Mediated Signaling Pathway
Protein-chromophore Linkage
Regulation Of Rhodopsin Mediated Signaling Pathway
Thermotaxis
Photoreceptor Cell Maintenance
Detection Of Temperature Stimulus Involved In Thermoception
Retina Development In Camera-type Eye
Cellular Response To Light Stimulus
Pathways
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Defective CFTR causes cystic fibrosis
E3 ubiquitin ligases ubiquitinate target proteins
The canonical retinoid cycle in rods (twilight vision)
Activation of the phototransduction cascade
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
G alpha (i) signalling events
Opsins
VxPx cargo-targeting to cilium
VxPx cargo-targeting to cilium
Drugs
Halothane
N-Acetylmethionine
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine
B-nonylglucoside
Phosphonothreonine
B-2-Octylglucoside
Hexadecanal
Palmitic Acid
Heptane-1,2,3-Triol
Dodecyldimethylamine N-oxide
(Hydroxyethyloxy)Tri(Ethyloxy)Octane
Heptyl 1-Thiohexopyranoside
Dexfosfoserine
Diseases
Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
Retinitis pigmentosa (RP)
Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
GWAS
Mean reticulocyte volume (
32888494
)
Metabolite levels (
23823483
)
Diisocyanate-induced asthma (
25918132
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
33 interacting genes:
ABHD4
AMFR
APP
AQP6
CFTR
CIAO2A
FCRL4
FFAR2
GAD2
HLA-A
KASH5
LMNA
LNX1
MELTF
REEP4
RETREG3
RHO
SCN3B
SELENOS
SLC10A1
SLC10A6
SLC30A8
SLC7A14
SLC7A8
TCF25
TEX44
TMED8
TMEM31
TMX2
TRIM32
UBE2J1
UBXN6
VCP
12 interacting genes:
ARR3
ARRB2
CD79A
DERL1
GNGT1
GRK1
GRK2
GRK5
GRK6
PPP2CA
PRKCA
SAG
Entrez ID
79139
6010
HPRD ID
12302
01584
Ensembl ID
ENSG00000136986
ENSG00000163914
Uniprot IDs
A0A024R9G3
E5RGY0
Q9BUN8
P08100
PDB IDs
5GLF
4ZWJ
5DGY
5W0P
6CMO
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?