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DERL1 and UBXN6
Data Source:
BioGRID
(pull down)
DERL1
UBXN6
Description
derlin 1
UBX domain protein 6
Image
GO Annotations
Cellular Component
Hrd1p Ubiquitin Ligase ERAD-L Complex
Early Endosome
Late Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1-VIMP Complex
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Nucleus
Cytoplasm
Lysosomal Membrane
Endosome
Microtubule Organizing Center
Cytosol
Extrinsic Component Of Membrane
Early Endosome Membrane
Late Endosome Membrane
Protein-containing Complex
Extracellular Exosome
Molecular Function
Protease Binding
Signal Recognition Particle Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Signaling Receptor Activity
MHC Class I Protein Binding
Identical Protein Binding
Protein-containing Complex Binding
ATPase Binding
Misfolded Protein Binding
Ubiquitin-specific Protease Binding
Protein Binding
Biological Process
Protein Folding
Response To Unfolded Protein
Viral Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Endoplasmic Reticulum Unfolded Protein Response
Retrograde Protein Transport, ER To Cytosol
Positive Regulation Of Protein Ubiquitination
Protein Destabilization
Positive Regulation Of Protein Binding
ERAD Pathway
Establishment Of Protein Localization
Transmembrane Transport
ER-associated Misfolded Protein Catabolic Process
Macroautophagy
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
ERAD Pathway
Pathways
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Defective CFTR causes cystic fibrosis
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Mean reticulocyte volume (
32888494
)
Metabolite levels (
23823483
)
Delta-5 desaturase activity response to n3-polyunsaturated fat supplement (
29246731
)
Multiple sclerosis (
31604244
)
Red blood cell count (
32888494
)
Interacting Genes
33 interacting genes:
ABHD4
AMFR
APP
AQP6
CFTR
CIAO2A
FCRL4
FFAR2
GAD2
HLA-A
KASH5
LMNA
LNX1
MELTF
REEP4
RETREG3
RHO
SCN3B
SELENOS
SLC10A1
SLC10A6
SLC30A8
SLC7A14
SLC7A8
TCF25
TEX44
TMED8
TMEM31
TMX2
TRIM32
UBE2J1
UBXN6
VCP
20 interacting genes:
APP
DAZAP2
DERL1
FAM168A
GSK3B
MAGEA4
MCL1
NLGN3
PLEKHB2
SMURF1
SUSD6
SVIP
TRIM39
UBC
UBXN10
UBXN2A
UBXN2B
UFD1
VCP
YOD1
Entrez ID
79139
80700
HPRD ID
12302
18253
Ensembl ID
ENSG00000136986
ENSG00000167671
Uniprot IDs
A0A024R9G3
E5RGY0
Q9BUN8
Q9BZV1
PDB IDs
5GLF
6SAP
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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