TMEM31 and VAMP3

Data Source:
BioGRID (two hybrid)

		TMEM31	VAMP3
Description		transmembrane protein 31	vesicle associated membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Early Endosome Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Secretory Granule Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding
	Biological Process		Positive Regulation Of Receptor Recycling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Positive Regulation Of Immunoglobulin Production Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Membrane Organization Membrane Fusion Protein-containing Complex Assembly Mucus Secretion Cellular Response To Interferon-gamma Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell
Pathways			ER-Phagosome pathway Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Morning vs. evening chronotype ( 26835600) Periodontal microbiota ( 22699663) Ulcerative colitis ( 28067908)
Interacting Genes		141 interacting genes: ABHD16A ABHD5 AGPAT4 AGTRAP ANKRD46 APOD ARV1 ATP5MC3 ATP6V0C BCAP31 BLCAP BMP10 BNIP1 BTN2A2 C14orf180 C2CD2L CAMLG CCL4 CGRRF1 CLDND2 CLN5 CLRN1 CMTM7 CNIH3 COX14 COX20 CTSA CTXN3 CXCL9 CXorf66 CYB561A3 CYB5R3 DEFB103A DEFB103B DEFB105A DEFB105B DERL1 DERL3 DGAT2L6 DHRSX DNAJC30 EBP EHHADH EMP1 ERG28 FAXDC2 FCER1G FKBP8 FXYD6 GIMAP5 GJB2 GJD4 GPR151 GUCA2A GYPA HERPUD2 HIGD1C HSD17B13 HSD3B7 IFITM5 ITGAM LHFPL5 LPAR3 LRAT LY6D MALL MFSD14B MMP14 MS4A1 NAT8 NINJ1 NINJ2 NSDHL ORMDL2 OTOP3 OTULINL PEDS1-UBE2V1 PLN PLP1 PLP2 PMP22 PNLIPRP1 PTPN1 RDH11 REEP2 RETREG3 RNF144A RNF19B RTP2 SELENOK SELENOM SERP2 SGTA SLC30A8 SLC35C2 SLC35E4 SLC39A6 SLC41A1 SLC66A2 SLC7A14 SMAGP SMIM1 SMIM3 SMPD2 SNORC SPTSSA STX12 STX5 SYNGR1 TEX264 TIMMDC1 TMBIM6 TMEM107 TMEM121 TMEM14A TMEM14C TMEM182 TMEM203 TMEM208 TMEM218 TMEM239 TMEM242 TMEM254 TMEM255B TMEM44 TMEM50A TMEM86A TMX2 TNFRSF10B TRARG1 TSPAN2 TVP23B UBE2J1 UBQLN1 UBQLN2 VAMP2 VAMP3 VAMP5 YIF1A YIPF6 ZFPL1	63 interacting genes: ACAP1 AHNAK2 AIG1 APP AQP6 ARL13B BCAP31 BCL2L13 BIK BSCL2 BSND CD79A CIAO2A CLDN7 CLEC14A COMT DDB1 DNAJC5 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B GORAB GPX8 IKBKG KCNK5 LHFPL5 LMNA MGST2 MGST3 NELFE NEMP1 PDZK1IP1 PLEKHO1 PTGES RETREG3 RMDN3 SAR1A SCN3B SLC10A1 SLC16A2 SNAP23 SNAP29 STX16 STX1A STX2 STX3 STX4 TM4SF19 TM4SF20 TMEM237 TMEM31 TMEM35A TMEM52B TMEM86B TMPPE TMX2 VAMP2 VAMP8 VEGFD VSIR
Entrez ID		203562	9341
HPRD ID		06652	04711
Ensembl ID		ENSG00000179363	ENSG00000049245
Uniprot IDs		A0A140VK58 Q5JXX7	Q15836 Q6FGG2
PDB IDs
Enriched GO Terms of Interacting Partners?
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