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TMEM31 and FCER1G
Data Source:
BioGRID
(two hybrid)
TMEM31
FCER1G
Description
transmembrane protein 31
Fc fragment of IgE receptor Ig
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Molecular Function
Protein Binding
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Identical Protein Binding
Biological Process
Stimulatory C-type Lectin Receptor Signaling Pathway
Neutrophil Activation Involved In Immune Response
T Cell Differentiation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Interleukin-4 Production
Fc-gamma Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Interleukin-3-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Phagocytosis
Leukocyte Migration
Cellular Response To Low-density Lipoprotein Particle Stimulus
Pathways
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Dectin-2 family
Dectin-2 family
Neutrophil degranulation
Platelet Adhesion to exposed collagen
Drugs
Benzylpenicilloyl polylysine
Diseases
GWAS
Aggressive periodontitis (
28449029
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
31361310
)
Allergy (
27182965
)
Asthma (
31361310
30929738
32296059
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Mean platelet volume (
32888494
27863252
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
White blood cell count (
32888494
)
Interacting Genes
141 interacting genes:
ABHD16A
ABHD5
AGPAT4
AGTRAP
ANKRD46
APOD
ARV1
ATP5MC3
ATP6V0C
BCAP31
BLCAP
BMP10
BNIP1
BTN2A2
C14orf180
C2CD2L
CAMLG
CCL4
CGRRF1
CLDND2
CLN5
CLRN1
CMTM7
CNIH3
COX14
COX20
CTSA
CTXN3
CXCL9
CXorf66
CYB561A3
CYB5R3
DEFB103A
DEFB103B
DEFB105A
DEFB105B
DERL1
DERL3
DGAT2L6
DHRSX
DNAJC30
EBP
EHHADH
EMP1
ERG28
FAXDC2
FCER1G
FKBP8
FXYD6
GIMAP5
GJB2
GJD4
GPR151
GUCA2A
GYPA
HERPUD2
HIGD1C
HSD17B13
HSD3B7
IFITM5
ITGAM
LHFPL5
LPAR3
LRAT
LY6D
MALL
MFSD14B
MMP14
MS4A1
NAT8
NINJ1
NINJ2
NSDHL
ORMDL2
OTOP3
OTULINL
PEDS1-UBE2V1
PLN
PLP1
PLP2
PMP22
PNLIPRP1
PTPN1
RDH11
REEP2
RETREG3
RNF144A
RNF19B
RTP2
SELENOK
SELENOM
SERP2
SGTA
SLC30A8
SLC35C2
SLC35E4
SLC39A6
SLC41A1
SLC66A2
SLC7A14
SMAGP
SMIM1
SMIM3
SMPD2
SNORC
SPTSSA
STX12
STX5
SYNGR1
TEX264
TIMMDC1
TMBIM6
TMEM107
TMEM121
TMEM14A
TMEM14C
TMEM182
TMEM203
TMEM208
TMEM218
TMEM239
TMEM242
TMEM254
TMEM255B
TMEM44
TMEM50A
TMEM86A
TMX2
TNFRSF10B
TRARG1
TSPAN2
TVP23B
UBE2J1
UBQLN1
UBQLN2
VAMP2
VAMP3
VAMP5
YIF1A
YIPF6
ZFPL1
83 interacting genes:
ADGRE2
C2CD2L
CDIPT
CERS4
CLCA4
CLEC4E
CNIH1
COX20
CYP4F2
DEFB127
DGAT2L6
EBP
FA2H
FAM209A
FAXDC2
FCER1A
FCGR3A
FFAR2
FUNDC2
FXYD6
GIMAP5
GJA5
GP6
GPR61
IER3IP1
KCNA1
KCNN3
KIR2DL4
LEPROTL1
LMNA
LNPEP
LYN
MFF
MGLL
NCR1
NCR3
NRM
ORMDL2
PDZK1IP1
PEMT
PEX16
PLCG2
PLP2
RUSF1
SEC22B
SFXN1
SFXN3
SLC10A1
SLC13A4
SLC18A1
SLC1A1
SLC30A8
SLC35G2
SLC38A7
SLC39A2
SLC39A9
SLC7A1
SLC7A14
SMIM1
STX12
SYK
SYNJ2BP
SYS1
THBD
TMEM107
TMEM120B
TMEM140
TMEM14B
TMEM179B
TMEM19
TMEM218
TMEM31
TPRG1
TSPO
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93A
VAMP1
YIF1A
YIPF4
YIPF6
Entrez ID
203562
2207
HPRD ID
06652
00916
Ensembl ID
ENSG00000179363
ENSG00000158869
Uniprot IDs
A0A140VK58
Q5JXX7
P30273
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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