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EMD and CISD2
Data Source:
BioGRID
(two hybrid)
EMD
CISD2
Description
emerin
CDGSH iron sulfur domain 2
Image
GO Annotations
Cellular Component
Nuclear Envelope
Nuclear Inner Membrane
Nuclear Outer Membrane
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Spindle
Microtubule
Membrane
Integral Component Of Membrane
Spindle Pole Centrosome
Nuclear Membrane
Cortical Endoplasmic Reticulum
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Protein-containing Complex
Perinuclear Endoplasmic Reticulum
Molecular Function
Actin Binding
Protein Binding
Cadherin Binding
Beta-tubulin Binding
RNA Binding
Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
2 Iron, 2 Sulfur Cluster Binding
Biological Process
Muscle Contraction
Mitotic Nuclear Envelope Reassembly
Muscle Organ Development
Skeletal Muscle Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Negative Regulation Of Fibroblast Proliferation
Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Growth Factor Stimulus
Nuclear Membrane Organization
Negative Regulation Of Canonical Wnt Signaling Pathway
Autophagy Of Mitochondrion
Multicellular Organism Aging
Regulation Of Autophagy
Pathways
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Depolymerisation of the Nuclear Lamina
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
Emery-Dreifuss muscular dystrophy
Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS
Mean spheric corpuscular volume (
32888494
)
Asthma and attention deficit hyperactivity disorder (
31619474
)
Estimated glomerular filtration rate (
31152163
)
Primary biliary cholangitis (
26394269
)
Schizophrenia (
28991256
)
Type 2 diabetes (
28869590
)
Interacting Genes
98 interacting genes:
ABL1
ABT1
ACTB
ACTG2
AEN
AKAP8L
ANK1
ANKS6
AVPI1
BANF1
BCLAF1
BEND7
BYSL
CATSPER1
CCDC33
CCNL2
CD33
CEP70
CERS4
CISD2
CLEC14A
COMT
COPS6
CPLX4
CREB3
CTNNBIP1
CXorf66
DPPA4
EFHC2
ERMAP
FAM209A
FATE1
GMCL1
GOLM2
GORAB
GPR152
GRAMD2A
HSF2BP
INCA1
KASH5
KCNJ12
KCNJ18
KCNJ8
KCNN3
KIF9
KIR2DL3
LIME1
LMNA
LMO7
LPL
LUZP4
MAB21L3
MAPK6
MEOX1
MEOX2
MMGT1
MRPL45
MTERF4
MTNR1A
NCAPH2
NF2
NPDC1
PAK5
PIMREG
PSME1
REL
RNASEH1
RNF123
SH3GL2
SH3GL3
SOWAHB
SRC
SSMEM1
STX1A
STX4
SYNE1
TCF23
TMEM174
TMEM200A
TMEM201
TMEM52B
TMEM80
TMX2
TRAF3IP3
TRIM42
VAPB
VAV1
YTHDC1
ZFP1
ZFP57
ZFP64
ZNF165
ZNF232
ZNF329
ZNF341
ZNF398
ZNF549
ZNF774
58 interacting genes:
AIG1
APOL2
APP
AQP10
BCL2L2
BET1
BMP10
BTN2A2
C14orf180
C2CD2L
C4orf3
CDIPT
CFHR5
CLDN10
CLN6
CYBC1
EHHADH
EMD
FAM241B
GALNT15
GAST
GPR37L1
HHATL
IER3
KIR2DL3
LEPROTL1
LRP10
MAN2B2
MIP
NAPB
NRG4
NSG1
PGAP2
PLPP4
PLPPR2
PNKP
POMGNT1
RTP2
RUSF1
SEC22A
SERP2
SLC13A3
SLC35B4
SMIM1
SNORC
SPP1
STX12
STX7
THSD7B
TMEM187
TMEM243
TMEM43
TMEM86A
TSPAN33
TTPA
VAMP4
VKORC1L1
YIPF6
Entrez ID
2010
493856
HPRD ID
02309
17413
Ensembl ID
ENSG00000102119
ENSG00000145354
Uniprot IDs
P50402
Q8N5K1
PDB IDs
1JEI
2ODC
2ODG
6GHD
6RPR
3FNV
4OO7
4OOA
Enriched GO Terms of Interacting Partners
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