CISD2 and SLC35B4

Data Source:
BioGRID (two hybrid)

		CISD2	SLC35B4
Description		CDGSH iron sulfur domain 2	solute carrier family 35 member B4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	UDP-N-acetylglucosamine Transmembrane Transporter Activity UDP-xylose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity
	Biological Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy	Regulation Of Gluconeogenesis Carbohydrate Transport UDP-xylose Transmembrane Transport UDP-N-acetylglucosamine Transmembrane Transport
Pathways			Transport of nucleotide sugars
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)	Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) Systolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	32 interacting genes: AQP6 CD79A CISD2 CLDN5 CPLX4 CREB3L1 EBAG9 ERGIC3 ERP29 FAM209A FAM210B FFAR2 GPR152 GPX8 HSD17B13 KASH5 LHFPL5 LMNA MMGT1 MUC1 PDZK1IP1 PVR RHBDL2 SCARA5 SLC18A1 STOM TBXA2R TMEM130 TMEM237 TMEM52B TYROBP VSIR
Entrez ID		493856	84912
HPRD ID		17413	11578
Ensembl ID		ENSG00000145354	ENSG00000205060
Uniprot IDs		Q8N5K1	Q969S0
PDB IDs		3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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