EMD and ZFP64

Data Source:
BioGRID (two hybrid)

		EMD	ZFP64
Description		emerin	ZFP64 zinc finger protein
Image
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Microtubule Membrane Integral Component Of Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum	Nucleus
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Muscle Contraction Mitotic Nuclear Envelope Reassembly Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway	Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS		Mean spheric corpuscular volume ( 32888494)	Adult body size ( 32376654) Amyotrophic lateral sclerosis ( 17362836) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Parkinson's disease ( 26227905) Reading disability or specific language impairment (pleiotropy) ( 25065397) Subcutaneous adipose tissue ( 22589738) Urinary metabolite levels in chronic kidney disease ( 29545352) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		98 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SOWAHB SRC SSMEM1 STX1A STX4 SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAPB VAV1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	27 interacting genes: AEN BARD1 BEGAIN BYSL EMD ERG28 FAM124A FHL2 L3MBTL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B PRPF31 RBM10 RHOU SETDB1 TAB2 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70
Entrez ID		2010	55734
HPRD ID		02309	15728
Ensembl ID		ENSG00000102119	ENSG00000020256
Uniprot IDs		P50402	B3KQX0 Q9NTW7
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR	1X5W 2DMD
Enriched GO Terms of Interacting Partners?
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