EMD and ZFP57

Data Source:
BioGRID (two hybrid)

		EMD	ZFP57
Description		emerin	ZFP57 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Microtubule Membrane Integral Component Of Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum	Nucleus
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Metal Ion Binding
	Biological Process	Muscle Contraction Mitotic Nuclear Envelope Reassembly Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II DNA Methylation Involved In Embryo Development
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Emery-Dreifuss muscular dystrophy	Transient neonatal diabetes mellitus (TNDM)
GWAS		Mean spheric corpuscular volume ( 32888494)	Albumin-globulin ratio ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Offspring birth weight ( 31043758) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		98 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SOWAHB SRC SSMEM1 STX1A STX4 SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAPB VAV1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	8 interacting genes: CIB3 DVL3 EMD KANK2 MKRN3 MLH1 POLR1C YOD1
Entrez ID		2010	346171
HPRD ID		02309	19560
Ensembl ID		ENSG00000102119	ENSG00000204644
Uniprot IDs		P50402	A0A1U9X8V5 B7ZW61 Q9NU63
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR
Enriched GO Terms of Interacting Partners?
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