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CISD2 and BCL2L2
Data Source:
BioGRID
(two hybrid)
CISD2
BCL2L2
Description
CDGSH iron sulfur domain 2
BCL2 like 2
Image
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Protein-containing Complex
Perinuclear Endoplasmic Reticulum
Mitochondrial Outer Membrane
Bcl-2 Family Protein Complex
Molecular Function
RNA Binding
Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
2 Iron, 2 Sulfur Cluster Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Disordered Domain Specific Binding
Biological Process
Autophagy Of Mitochondrion
Multicellular Organism Aging
Regulation Of Autophagy
Spermatogenesis
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Apoptotic Process
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Navitoclax
Diseases
Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS
Asthma and attention deficit hyperactivity disorder (
31619474
)
Estimated glomerular filtration rate (
31152163
)
Primary biliary cholangitis (
26394269
)
Schizophrenia (
28991256
)
Type 2 diabetes (
28869590
)
Height (
28552196
)
Interacting Genes
58 interacting genes:
AIG1
APOL2
APP
AQP10
BCL2L2
BET1
BMP10
BTN2A2
C14orf180
C2CD2L
C4orf3
CDIPT
CFHR5
CLDN10
CLN6
CYBC1
EHHADH
EMD
FAM241B
GALNT15
GAST
GPR37L1
HHATL
IER3
KIR2DL3
LEPROTL1
LRP10
MAN2B2
MIP
NAPB
NRG4
NSG1
PGAP2
PLPP4
PLPPR2
PNKP
POMGNT1
RTP2
RUSF1
SEC22A
SERP2
SLC13A3
SLC35B4
SMIM1
SNORC
SPP1
STX12
STX7
THSD7B
TMEM187
TMEM243
TMEM43
TMEM86A
TSPAN33
TTPA
VAMP4
VKORC1L1
YIPF6
53 interacting genes:
ANKS6
APOC1
APOC2
APOC4
ATP5PF
BAD
BAK1
BAX
BBC3
BCL2L11
BHLHA9
BID
BIK
BMF
BNIP3
BNIP5
C10orf67
CD79A
CHODL
CIDEB
CISD2
CLDN7
ERVFRD-1
FATE1
G0S2
GORAB
GPR151
GPX8
HRK
KASH5
KCNJ6
LMNA
LRRIQ1
MGST2
MUC1
PANX1
PPP1CA
PSCA
RHBDD2
S100B
SAR1A
SGPL1
SLC35C2
SLC35E3
SLC39A2
SLC39A6
STOM
SUSD3
TCF4
TEX11
TMEM139
TMX1
TP53
Entrez ID
493856
599
HPRD ID
17413
03569
Ensembl ID
ENSG00000145354
ENSG00000129473
Uniprot IDs
Q8N5K1
Q92843
PDB IDs
3FNV
4OO7
4OOA
1MK3
1O0L
1ZY3
2Y6W
4CIM
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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