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CISD2 and BMP10
Data Source:
BioGRID
(two hybrid)
CISD2
BMP10
Description
CDGSH iron sulfur domain 2
bone morphogenetic protein 10
Image
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Protein-containing Complex
Perinuclear Endoplasmic Reticulum
Extracellular Region
Extracellular Space
Cytoplasm
Cell Surface
Z Disc
Molecular Function
RNA Binding
Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
2 Iron, 2 Sulfur Cluster Binding
Cytokine Activity
Hormone Activity
Protein Binding
Growth Factor Activity
Telethonin Binding
Receptor Serine/threonine Kinase Binding
Biological Process
Autophagy Of Mitochondrion
Multicellular Organism Aging
Regulation Of Autophagy
Kidney Development
Cell Adhesion
Adult Heart Development
Negative Regulation Of Endothelial Cell Migration
Positive Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
Negative Regulation Of Cell Migration
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Sarcomere Organization
Positive Regulation Of Transcription, DNA-templated
Atrial Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Cell Development
Regulation Of Cardiac Muscle Contraction
Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of Sarcomere Organization
Heart Trabecula Formation
Pathway-restricted SMAD Protein Phosphorylation
SMAD Protein Signal Transduction
Positive Regulation Of Cartilage Development
Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways
Signaling by BMP
Molecules associated with elastic fibres
Drugs
Diseases
Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS
Asthma and attention deficit hyperactivity disorder (
31619474
)
Estimated glomerular filtration rate (
31152163
)
Primary biliary cholangitis (
26394269
)
Schizophrenia (
28991256
)
Type 2 diabetes (
28869590
)
Interacting Genes
58 interacting genes:
AIG1
APOL2
APP
AQP10
BCL2L2
BET1
BMP10
BTN2A2
C14orf180
C2CD2L
C4orf3
CDIPT
CFHR5
CLDN10
CLN6
CYBC1
EHHADH
EMD
FAM241B
GALNT15
GAST
GPR37L1
HHATL
IER3
KIR2DL3
LEPROTL1
LRP10
MAN2B2
MIP
NAPB
NRG4
NSG1
PGAP2
PLPP4
PLPPR2
PNKP
POMGNT1
RTP2
RUSF1
SEC22A
SERP2
SLC13A3
SLC35B4
SMIM1
SNORC
SPP1
STX12
STX7
THSD7B
TMEM187
TMEM243
TMEM43
TMEM86A
TSPAN33
TTPA
VAMP4
VKORC1L1
YIPF6
59 interacting genes:
ACVR2A
ACVR2B
APOA5
AQP6
ARL13B
BIK
BMPR2
BSCL2
BSND
CCDC70
CD33
CISD2
CLDN7
COQ9
CREB3L1
DEXI
EBP
ERP29
FAM209A
FCGR1A
FCRL4
FFAR2
FKBP7
FNDC9
GGT6
GJB1
GPR152
GPX8
IL3RA
JAGN1
KIR2DL3
KIR3DL1
KLRC1
LRRC25
LRRC4C
MGST3
MRPS18B
MS4A3
MTIF3
PLPP4
REEP4
SERINC3
SIT1
SLC10A1
SLC10A6
SLC35C2
SLC38A1
SLC4A1
SPAG4
TCTA
TMEM14B
TMEM31
TMEM45B
TMEM86B
TMPRSS2
TNFSF14
TNFSF8
TSPAN31
VSIR
Entrez ID
493856
27302
HPRD ID
17413
09788
Ensembl ID
ENSG00000145354
ENSG00000163217
Uniprot IDs
Q8N5K1
O95393
PDB IDs
3FNV
4OO7
4OOA
6SF1
6SF3
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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