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EMD and TMEM52B
Data Source:
BioGRID
(two hybrid)
EMD
TMEM52B
Description
emerin
transmembrane protein 52B
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Nuclear Inner Membrane
Nuclear Outer Membrane
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Spindle
Microtubule
Membrane
Integral Component Of Membrane
Spindle Pole Centrosome
Nuclear Membrane
Cortical Endoplasmic Reticulum
Integral Component Of Membrane
Extracellular Exosome
Molecular Function
Actin Binding
Protein Binding
Cadherin Binding
Beta-tubulin Binding
Molecular_function
Protein Binding
Biological Process
Muscle Contraction
Mitotic Nuclear Envelope Reassembly
Muscle Organ Development
Skeletal Muscle Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Negative Regulation Of Fibroblast Proliferation
Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Growth Factor Stimulus
Nuclear Membrane Organization
Negative Regulation Of Canonical Wnt Signaling Pathway
Biological_process
Pathways
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Depolymerisation of the Nuclear Lamina
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
Emery-Dreifuss muscular dystrophy
GWAS
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
98 interacting genes:
ABL1
ABT1
ACTB
ACTG2
AEN
AKAP8L
ANK1
ANKS6
AVPI1
BANF1
BCLAF1
BEND7
BYSL
CATSPER1
CCDC33
CCNL2
CD33
CEP70
CERS4
CISD2
CLEC14A
COMT
COPS6
CPLX4
CREB3
CTNNBIP1
CXorf66
DPPA4
EFHC2
ERMAP
FAM209A
FATE1
GMCL1
GOLM2
GORAB
GPR152
GRAMD2A
HSF2BP
INCA1
KASH5
KCNJ12
KCNJ18
KCNJ8
KCNN3
KIF9
KIR2DL3
LIME1
LMNA
LMO7
LPL
LUZP4
MAB21L3
MAPK6
MEOX1
MEOX2
MMGT1
MRPL45
MTERF4
MTNR1A
NCAPH2
NF2
NPDC1
PAK5
PIMREG
PSME1
REL
RNASEH1
RNF123
SH3GL2
SH3GL3
SOWAHB
SRC
SSMEM1
STX1A
STX4
SYNE1
TCF23
TMEM174
TMEM200A
TMEM201
TMEM52B
TMEM80
TMX2
TRAF3IP3
TRIM42
VAPB
VAV1
YTHDC1
ZFP1
ZFP57
ZFP64
ZNF165
ZNF232
ZNF329
ZNF341
ZNF398
ZNF549
ZNF774
68 interacting genes:
ALG3
APOD
APOL2
APOL3
BET1
BTN2A2
C1GALT1
C3orf52
CLDN19
CLDN4
CNIH1
CNIH3
CSGALNACT2
DNAJC30
EMD
FXYD3
GAST
GPR25
GPR37L1
IGFBP5
INSIG2
ITGAM
JAGN1
LHFPL5
LPAR3
LTC4S
MAL
MARCHF2
MIP
MS4A13
NINJ2
NRM
NSG1
ORMDL1
PEDS1-UBE2V1
PGAP2
PLN
PLP1
RTP2
SEC22A
SERP1
SLC30A2
SLC30A8
SLC35A4
SLC35B4
SLC38A7
SMIM1
TF
TMEM100
TMEM107
TMEM109
TMEM128
TMEM147
TMEM14C
TMEM203
TMEM218
TMEM267
TMEM50B
TMEM54
TMEM60
TMEM86B
TMEM97
TMUB2
TRAM1L1
TRARG1
VAMP3
VAMP5
ZDHHC15
Entrez ID
2010
120939
HPRD ID
02309
08709
Ensembl ID
ENSG00000102119
ENSG00000165685
Uniprot IDs
P50402
Q4KMG9
PDB IDs
1JEI
2ODC
2ODG
6GHD
6RPR
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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