CISD2 and FAM241B

Data Source:
BioGRID (two hybrid)

		CISD2	FAM241B
Description		CDGSH iron sulfur domain 2	family with sequence similarity 241 member B
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding
	Biological Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)	Type 2 diabetes ( 30054458)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	27 interacting genes: ADRA1A BIK BLCAP BNIP3 CD79A CGRRF1 CISD2 ERBB2 ERBB3 ERBB4 HSD17B11 KASH5 MOSPD1 MTNR1A REEP4 RNF185 RNF5 SCN3B SLC10A1 SLC39A11 SLC7A1 SUSD6 SYNE4 TMEM234 TMX2 TRHR ZDHHC15
Entrez ID		493856	219738
HPRD ID		17413	12573
Ensembl ID		ENSG00000145354	ENSG00000171224
Uniprot IDs		Q8N5K1	A0A024QZL0 Q96D05
PDB IDs		3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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