TYMP and MESD

Data Source:
BioGRID (two hybrid)

		TYMP	MESD
Description		thymidine phosphorylase	mesoderm development LRP chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Endoplasmic Reticulum Plasma Membrane
	Molecular Function	1,4-alpha-oligoglucan Phosphorylase Activity Protein Binding Growth Factor Activity Thymidine Phosphorylase Activity Pyrimidine-nucleoside Phosphorylase Activity Protein Homodimerization Activity	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Mitochondrial Genome Maintenance Angiogenesis Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleoside Metabolic Process Chemotaxis Signal Transduction Cell Differentiation Regulation Of Myelination Pyrimidine Nucleoside Salvage DTMP Catabolic Process Pyrimidine Nucleoside Catabolic Process Regulation Of Transmission Of Nerve Impulse Regulation Of Gastric Motility	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		Pyrimidine salvage Pyrimidine catabolism
Drugs		Tipiracil
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 30072576) Chronic lymphocytic leukemia ( 28165464) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494 20139978 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494 27863252) Red blood cell traits ( 23222517) Red cell distribution width ( 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: ERBB2 LINC01554 MESD ZMYND12	75 interacting genes: ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SIK1B SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844
Entrez ID		1890	23184
HPRD ID		08833	12129
Ensembl ID		ENSG00000025708	ENSG00000117899
Uniprot IDs		B2RBL3 E5KRG5 P19971	Q14696
PDB IDs		1UOU 2J0F 2WK5 2WK6
Enriched GO Terms of Interacting Partners?
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