Description |
ubiquitin specific peptidase 54 |
proprotein convertase subtilisin/kexin type 5 |
Image |
No pdb structure |
No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
- Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
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- Alzheimer's disease progression score ( 29860282)
- Amyotrophic lateral sclerosis (age of onset) ( 22959728)
- Ankylosing spondylitis ( 30946743)
- Apolipoprotein B levels ( 32203549)
- Body fat distribution (leg fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Diverticular disease ( 30177863)
- Glucocorticoid-induced osteonecrosis ( 26265699)
- Glucose homeostasis traits ( 25524916)
- Height ( 28552196 20881960 25282103 23563607 31562340)
- Hypotension and cognitive impairment ( 31362389)
- Inflammatory bowel disease ( 27569725)
- Intraocular pressure ( 29785010 31959993 30054594)
- LDL cholesterol levels ( 32203549)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Lead levels ( 26025379)
- Low density lipoprotein cholesterol levels ( 32154731)
- Male fertility ( 22633400)
- Metabolite levels (5-HIAA) ( 23319000)
- Pursuit maintenance gain ( 29064472)
- Response to fenofibrate (adiponectin levels) ( 23149075)
- Systemic sclerosis ( 30247649)
- Takayasu arteritis ( 25604533)
- Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
- Vascular brain injury ( 25188341)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412)
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Interacting Genes |
88 interacting genes:
ANKRD11
ANKS1A
ARMC7
ATN1
ATXN1
ATXN1L
ATXN7L2
BFSP2
BHLHE40
CARD10
CCDC13
CCDC24
CCNK
CDC23
CHCHD2
CHERP
CHMP1B
CHMP2A
CHMP2B
CHMP4C
CSTF2
CYSRT1
DMRT3
DOK6
DTX2
EIF4E2
EPM2AIP1
EXOC8
FAM124B
FBXO17
FNDC3B
FOXI1
GCM2
HGS
HNF1B
HNRNPF
HOXC8
IGFN1
INSC
KCTD9
LMO3
LNX1
MED25
MID2
NUDT22
NXT2
OIP5
OTX1
PCSK5
PHF1
PLA2G6
PLAC8
PLEKHN1
POLR1C
PRDM6
PRKAB2
PRR35
QRICH1
RACK1
RAMAC
RBPMS2
RHOBTB3
RNF208
SEC24A
SHARPIN
SHC3
SMARCD1
SMYD1
SNRPB
SS18L1
STK16
TBX6
TCEA2
TEKT5
TENT5B
TFAP2D
TLE5
TNS2
TOLLIP
TSEN15
TSSK3
TTC19
UBC
USP2
VENTX
ZCCHC14
ZNF148
ZNF76
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69 interacting genes:
ADAMTSL4
AMH
APPBP2
ATN1
C17orf50
C22orf39
CACNA1A
CCDC33
CREB5
CYSRT1
DBF4B
DOCK2
FAM86C1P
FARS2
FRS3
GLRX3
GUCD1
HOXA1
HOXB9
INCA1
ITGA6
KRTAP1-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP13-3
KRTAP19-2
KRTAP3-1
KRTAP3-2
KRTAP4-12
KRTAP5-9
LCE1D
LCE1F
LCE2C
LCE3C
LCE3D
MDFI
MEOX2
NBPF19
NOTCH2NLA
NR1D2
NR4A3
NUFIP2
OTX1
PCSK6
PLSCR4
PMCH
POU4F2
PTPRM
REN
SHFL
SMCP
SPRY1
SSC4D
STK16
TEKT4
TLE5
TRAF4
TRIB3
TRIM42
TRIP13
USP54
VGLL3
ZNF547
ZNF655
ZNF837
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Entrez ID |
159195 |
5125 |
HPRD ID |
15641 |
08985 |
Ensembl ID |
ENSG00000166348
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ENSG00000099139
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Uniprot IDs |
B7Z7X1
Q70EL1
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Q92824
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PDB IDs |
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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