Description |
proprotein convertase subtilisin/kexin type 5 |
phospholipid scramblase 4 |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alzheimer's disease progression score ( 29860282)
- Amyotrophic lateral sclerosis (age of onset) ( 22959728)
- Ankylosing spondylitis ( 30946743)
- Apolipoprotein B levels ( 32203549)
- Body fat distribution (leg fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Diverticular disease ( 30177863)
- Glucocorticoid-induced osteonecrosis ( 26265699)
- Glucose homeostasis traits ( 25524916)
- Height ( 28552196 20881960 25282103 23563607 31562340)
- Hypotension and cognitive impairment ( 31362389)
- Inflammatory bowel disease ( 27569725)
- Intraocular pressure ( 29785010 31959993 30054594)
- LDL cholesterol levels ( 32203549)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Lead levels ( 26025379)
- Low density lipoprotein cholesterol levels ( 32154731)
- Male fertility ( 22633400)
- Metabolite levels (5-HIAA) ( 23319000)
- Pursuit maintenance gain ( 29064472)
- Response to fenofibrate (adiponectin levels) ( 23149075)
- Systemic sclerosis ( 30247649)
- Takayasu arteritis ( 25604533)
- Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
- Vascular brain injury ( 25188341)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412)
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Interacting Genes |
69 interacting genes:
ADAMTSL4
AMH
APPBP2
ATN1
C17orf50
C22orf39
CACNA1A
CCDC33
CREB5
CYSRT1
DBF4B
DOCK2
FAM86C1P
FARS2
FRS3
GLRX3
GUCD1
HOXA1
HOXB9
INCA1
ITGA6
KRTAP1-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP13-3
KRTAP19-2
KRTAP3-1
KRTAP3-2
KRTAP4-12
KRTAP5-9
LCE1D
LCE1F
LCE2C
LCE3C
LCE3D
MDFI
MEOX2
NBPF19
NOTCH2NLA
NR1D2
NR4A3
NUFIP2
OTX1
PCSK6
PLSCR4
PMCH
POU4F2
PTPRM
REN
SHFL
SMCP
SPRY1
SSC4D
STK16
TEKT4
TLE5
TRAF4
TRIB3
TRIM42
TRIP13
USP54
VGLL3
ZNF547
ZNF655
ZNF837
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62 interacting genes:
ABHD17A
ADAMTSL4
APLN
ATP23
C11orf1
CES1
CLPP
CRCT1
DAZAP2
DDIT4L
EFEMP2
FCHO1
GATA1
HDHD3
HOXA1
INTS11
ITGB4
KLHL38
KPRP
KRT82
KRTAP1-5
KRTAP10-8
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP19-7
KRTAP21-2
KRTAP3-1
KRTAP3-3
KRTAP4-12
KRTAP4-2
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP8-1
LCE1A
LCE1C
LCE2B
LCE5A
LPXN
MTUS2
NID2
NOTCH2NLA
OXER1
PCSK5
PLSCR1
RAMAC
RBP3
RBPMS
RPS27A
SLC15A2
SSC4D
TEKT5
TENM4
TRIM42
TRIP13
TSPAN4
UBA52
UBB
UBC
YPEL3
ZNF34
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Entrez ID |
5125 |
57088 |
HPRD ID |
08985 |
07401 |
Ensembl ID |
ENSG00000099139
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ENSG00000114698
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Uniprot IDs |
Q92824
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E9PHR9
Q9NRQ2
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PDB IDs |
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3Q5U
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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