USP54 and SMYD1

Data Source:
BioGRID (two hybrid)

		USP54	SMYD1
Description		ubiquitin specific peptidase 54	SET and MYND domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)
Interacting Genes		88 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76	44 interacting genes: ARID5A BACH2 BHLHE40 C11orf1 C11orf16 C11orf53 CCDC113 CCDC33 DISC1 DVL1 FAM166A FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44
Entrez ID		159195	150572
HPRD ID		15641	06025
Ensembl ID		ENSG00000166348	ENSG00000115593
Uniprot IDs		B7Z7X1 Q70EL1	E9PHG3 Q5HYE8 Q8NB12
PDB IDs
Enriched GO Terms of Interacting Partners?
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