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CLTC and XRCC6
Data Source:
HPRD
(two hybrid)
CLTC
XRCC6
Description
clathrin heavy chain
X-ray repair cross complementing 6
Image
GO Annotations
Cellular Component
Lysosome
Endosome
Spindle
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Clathrin Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Clathrin-coated Vesicle
Clathrin-coated Endocytic Vesicle Membrane
Trans-Golgi Network Membrane
Protein-containing Complex
Endolysosome Membrane
Melanosome
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Clathrin Complex
Mitotic Spindle
Extracellular Vesicle
Mitotic Spindle Microtubule
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Extracellular Region
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nucleolus
Cytosol
Membrane
Protein-containing Complex
Protein-DNA Complex
Secretory Granule Lumen
Ku70:Ku80 Complex
Nonhomologous End Joining Complex
Ficolin-1-rich Granule Lumen
Molecular Function
RNA Binding
Double-stranded RNA Binding
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Clathrin Light Chain Binding
Low-density Lipoprotein Particle Receptor Binding
Disordered Domain Specific Binding
Ubiquitin-specific Protease Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA Helicase Activity
Damaged DNA Binding
Double-stranded DNA Binding
Double-stranded Telomeric DNA Binding
RNA Binding
Protein Binding
ATP Binding
Protein C-terminus Binding
DNA-dependent ATPase Activity
Cyclin Binding
Telomeric DNA Binding
Protein-containing Complex Binding
DNA End Binding
5'-deoxyribose-5-phosphate Lyase Activity
Biological Process
Mitotic Cell Cycle
Osteoblast Differentiation
Intracellular Protein Transport
Receptor-mediated Endocytosis
Autophagy
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Low-density Lipoprotein Particle Receptor Catabolic Process
Transferrin Transport
Low-density Lipoprotein Particle Clearance
Retrograde Transport, Endosome To Golgi
Clathrin Coat Assembly
Cell Division
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Mitotic Spindle Organization
Membrane Organization
Clathrin-dependent Endocytosis
Amyloid-beta Clearance By Transcytosis
Negative Regulation Of Hyaluronan Biosynthetic Process
Negative Regulation Of Protein Localization To Plasma Membrane
Telomere Maintenance
Activation Of Innate Immune Response
DNA Ligation
Double-strand Break Repair Via Nonhomologous End Joining
DNA Recombination
Brain Development
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Lymphocyte Differentiation
Positive Regulation Of Protein Kinase Activity
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Smooth Muscle Cell Proliferation
Cellular Hyperosmotic Salinity Response
Cellular Response To Gamma Radiation
Cellular Response To X-ray
Establishment Of Integrated Proviral Latency
Double-strand Break Repair Via Classical Nonhomologous End Joining
Pathways
Entry of Influenza Virion into Host Cell via Endocytosis
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
2-LTR circle formation
Cytosolic sensors of pathogen-associated DNA
IRF3-mediated induction of type I IFN
Nonhomologous End-Joining (NHEJ)
Neutrophil degranulation
Drugs
Diseases
GWAS
Breast cancer (
29059683
)
Meat-related diet (
32066663
)
Neuroticism (
29255261
)
Pulse pressure (
28135244
)
Refractive error (
32231278
)
Interacting Genes
61 interacting genes:
ACO1
AFTPH
AMPH
AP1B1
AP1G1
AP3B1
AP3B2
ARMCX3
ARR3
ARRB1
ARRB2
C10orf88
CLINT1
CLTA
CLTB
DNAJC6
DUX4
EPN1
EPN2
ERG
FYN
GAK
GGA1
GGA2
GGA3
GRIN1
GRIN2D
HGS
HIP1
HIP1R
ITSN1
KIT
LDLRAP1
MAP3K10
NCALD
NDRG1
OCRL
OPTN
PICALM
PPP1CA
PPP1CC
PRKACA
PXN
QARS1
SCYL2
SMAP1
SNX5
SNX9
SRC
STAMBP
SUMO2
SYNJ1
TFAP2A
TNK2
TOM1
VCL
WNK1
XRCC6
YWHAG
YWHAQ
ZFYVE9
135 interacting genes:
ABCD4
ABL1
ACD
ADCY7
APEX1
AR
ARAP1
ATP23
ATP6V1E1
BARD1
BAZ1A
BTG1
CAPN11
CBX5
CCNA1
CCT3
CD40
CDCA5
CDK2
CDKN1A
CEBPA
CENPU
CHAF1A
CHEK1
CLTC
CLU
CMTM6
COIL
COPB1
CREBBP
CSNK2A1
CTBP2
DLX2
DNTT
DUX4
DYSF
EFNA1
EGFR
EID1
ELF3
EP300
EPS8
ETS1
FMNL1
GAL3ST4
GSE1
GZMA
GZMB
HERPUD1
HMGA2
HOXB7
HOXC4
HOXD4
HSF1
HTT
ILVBL
JPT2
KAT2A
KAT2B
KIAA0408
LIG3
MAP2K5
MAP4K2
MAPK8
MRE11
MSX2
NAA15
NCF4
NCL
NCOA6
NIT1
NOTCH1
PAEP
PAFAH1B3
PARP1
PCNA
PDK1
PDPK1
PDX1
PECAM1
PGAM1
PGR
PIN1
PLGRKT
PNRC2
POR
POU2F1
POU2F2
PRKDC
PRPF40A
PTEN
PTTG1
QRSL1
RASA1
RBBP4
RGS2
RNF126
RNF146
RPLP1
RPS10
RRAS2
RUNX2
SDHC
SELENOF
SERPINA2
SERPINB9
SET
SGO1
SIRT3
SKIL
SMAD3
SMAD7
SNTA1
SNU13
SPARC
SUMO2
TAC1
TADA3
TBCD
TCF4
TERF2
TERF2IP
TERT
TOP1
TP53
UBC
USP14
VAV1
VBP1
WBP4
WRN
XRCC5
YWHAZ
ZBTB7A
ZNF512B
Entrez ID
1213
2547
HPRD ID
00350
01071
Ensembl ID
ENSG00000141367
ENSG00000196419
Uniprot IDs
A0A087WVQ6
Q00610
A0A024R1N4
B1AHC9
B4DE32
B4E356
P12956
PDB IDs
2XZG
4G55
6E4L
6QNN
6QNP
1JEQ
1JEY
1JJR
3RZX
5Y3R
6ERF
6ERG
6ERH
6ZHA
6ZHE
Enriched GO Terms of Interacting Partners
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