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CLTC and SNX5
Data Source:
BioGRID
(two hybrid)
CLTC
SNX5
Description
clathrin heavy chain
sorting nexin 5
Image
GO Annotations
Cellular Component
Lysosome
Endosome
Spindle
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Clathrin Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Clathrin-coated Vesicle
Clathrin-coated Endocytic Vesicle Membrane
Trans-Golgi Network Membrane
Protein-containing Complex
Endolysosome Membrane
Melanosome
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Clathrin Complex
Mitotic Spindle
Extracellular Vesicle
Mitotic Spindle Microtubule
Ruffle
Phagocytic Cup
Endosome
Cytosol
Brush Border
Cytoplasmic Vesicle Membrane
Retromer Complex
Retromer, Tubulation Complex
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Extrinsic Component Of Endosome Membrane
Early Endosome Membrane
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Macropinocytic Cup
Tubular Endosome
Molecular Function
RNA Binding
Double-stranded RNA Binding
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Clathrin Light Chain Binding
Low-density Lipoprotein Particle Receptor Binding
Disordered Domain Specific Binding
Ubiquitin-specific Protease Binding
Protein Binding
Phosphatidylinositol-5-phosphate Binding
D1 Dopamine Receptor Binding
Dynactin Binding
Phosphatidylinositol Binding
Cadherin Binding
Phosphatidylinositol-4-phosphate Binding
Phosphatidylinositol-3,5-bisphosphate Binding
Biological Process
Mitotic Cell Cycle
Osteoblast Differentiation
Intracellular Protein Transport
Receptor-mediated Endocytosis
Autophagy
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Low-density Lipoprotein Particle Receptor Catabolic Process
Transferrin Transport
Low-density Lipoprotein Particle Clearance
Retrograde Transport, Endosome To Golgi
Clathrin Coat Assembly
Cell Division
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Mitotic Spindle Organization
Membrane Organization
Clathrin-dependent Endocytosis
Amyloid-beta Clearance By Transcytosis
Negative Regulation Of Hyaluronan Biosynthetic Process
Negative Regulation Of Protein Localization To Plasma Membrane
Intracellular Protein Transport
Pinocytosis
Epidermal Growth Factor Catabolic Process
Regulation Of Macroautophagy
Positive Regulation Of Renal Sodium Excretion
Retrograde Transport, Endosome To Golgi
Negative Regulation Of Blood Pressure
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Insulin Receptor Signaling Pathway
Pathways
Entry of Influenza Virion into Host Cell via Endocytosis
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Apolipoprotein B levels (
32203549
)
Cholesterol, total (
25961943
)
LDL cholesterol (
24097068
25961943
)
LDL cholesterol levels (
32203549
28334899
30698716
)
LDL cholesterol levels in current drinkers (
30698716
)
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) (
30698716
)
Interacting Genes
61 interacting genes:
ACO1
AFTPH
AMPH
AP1B1
AP1G1
AP3B1
AP3B2
ARMCX3
ARR3
ARRB1
ARRB2
C10orf88
CLINT1
CLTA
CLTB
DNAJC6
DUX4
EPN1
EPN2
ERG
FYN
GAK
GGA1
GGA2
GGA3
GRIN1
GRIN2D
HGS
HIP1
HIP1R
ITSN1
KIT
LDLRAP1
MAP3K10
NCALD
NDRG1
OCRL
OPTN
PICALM
PPP1CA
PPP1CC
PRKACA
PXN
QARS1
SCYL2
SMAP1
SNX5
SNX9
SRC
STAMBP
SUMO2
SYNJ1
TFAP2A
TNK2
TOM1
VCL
WNK1
XRCC6
YWHAG
YWHAQ
ZFYVE9
19 interacting genes:
APPBP2
AQP2
BANP
CDC37
CLTC
CLTCL1
DDX58
DNAJB11
FANCA
HGS
HMOX2
ITSN1
LAMTOR5
MESD
MIB1
PFDN1
PRKRA
PSMB8
SNX2
Entrez ID
1213
27131
HPRD ID
00350
10439
Ensembl ID
ENSG00000141367
ENSG00000089006
Uniprot IDs
A0A087WVQ6
Q00610
Q6P5V6
Q9Y5X3
PDB IDs
2XZG
4G55
6E4L
6QNN
6QNP
1SYS
5TGH
5TGI
5TGJ
5WY2
6N5X
6N5Y
6N5Z
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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