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CLTC and CLTA
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, proximity labelling technology)
HPRD
(two hybrid, in vitro)
CLTC
CLTA
Description
clathrin heavy chain
clathrin light chain A
Image
GO Annotations
Cellular Component
Lysosome
Endosome
Spindle
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Clathrin Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Clathrin-coated Vesicle
Clathrin-coated Endocytic Vesicle Membrane
Trans-Golgi Network Membrane
Protein-containing Complex
Endolysosome Membrane
Melanosome
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Clathrin Complex
Mitotic Spindle
Extracellular Vesicle
Mitotic Spindle Microtubule
Spindle
Cytosol
Plasma Membrane
Membrane
Clathrin Coat
Clathrin Vesicle Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Synaptic Vesicle Membrane
Cytoplasmic Vesicle
Trans-Golgi Network Membrane
Endolysosome Membrane
Clathrin-coated Endocytic Vesicle
Clathrin Complex
Presynaptic Endocytic Zone Membrane
Postsynaptic Endocytic Zone Cytoplasmic Component
Molecular Function
RNA Binding
Double-stranded RNA Binding
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Clathrin Light Chain Binding
Low-density Lipoprotein Particle Receptor Binding
Disordered Domain Specific Binding
Ubiquitin-specific Protease Binding
Molecular_function
Structural Molecule Activity
Protein Binding
Clathrin Heavy Chain Binding
Peptide Binding
Protein-containing Complex Binding
GTPase Binding
Biological Process
Mitotic Cell Cycle
Osteoblast Differentiation
Intracellular Protein Transport
Receptor-mediated Endocytosis
Autophagy
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Low-density Lipoprotein Particle Receptor Catabolic Process
Transferrin Transport
Low-density Lipoprotein Particle Clearance
Retrograde Transport, Endosome To Golgi
Clathrin Coat Assembly
Cell Division
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Mitotic Spindle Organization
Membrane Organization
Clathrin-dependent Endocytosis
Amyloid-beta Clearance By Transcytosis
Negative Regulation Of Hyaluronan Biosynthetic Process
Negative Regulation Of Protein Localization To Plasma Membrane
Intracellular Protein Transport
Cell Cycle
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Low-density Lipoprotein Particle Receptor Catabolic Process
Low-density Lipoprotein Particle Clearance
Clathrin Coat Assembly
Cell Division
Membrane Organization
Clathrin-dependent Endocytosis
Pathways
Entry of Influenza Virion into Host Cell via Endocytosis
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Entry of Influenza Virion into Host Cell via Endocytosis
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Drugs
Diseases
GWAS
Bipolar disorder (inflammation and infection response interaction) (
25781172
)
Bisphosphonate-associated atypical femoral fracture (
31006051
)
Interacting Genes
61 interacting genes:
ACO1
AFTPH
AMPH
AP1B1
AP1G1
AP3B1
AP3B2
ARMCX3
ARR3
ARRB1
ARRB2
C10orf88
CLINT1
CLTA
CLTB
DNAJC6
DUX4
EPN1
EPN2
ERG
FYN
GAK
GGA1
GGA2
GGA3
GRIN1
GRIN2D
HGS
HIP1
HIP1R
ITSN1
KIT
LDLRAP1
MAP3K10
NCALD
NDRG1
OCRL
OPTN
PICALM
PPP1CA
PPP1CC
PRKACA
PXN
QARS1
SCYL2
SMAP1
SNX5
SNX9
SRC
STAMBP
SUMO2
SYNJ1
TFAP2A
TNK2
TOM1
VCL
WNK1
XRCC6
YWHAG
YWHAQ
ZFYVE9
8 interacting genes:
CLTC
EGFR
HIP1
HIP1R
HSPA8
MAP1LC3B
RGS2
SYNJ1
Entrez ID
1213
1211
HPRD ID
00350
00351
Ensembl ID
ENSG00000141367
ENSG00000122705
Uniprot IDs
A0A087WVQ6
Q00610
C9J8P9
P09496
PDB IDs
2XZG
4G55
6E4L
6QNN
6QNP
6E5N
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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