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LZTS1 and AGTR1
Data Source:
BioGRID
(two hybrid)
LZTS1
AGTR1
Description
leucine zipper tumor suppressor 1
angiotensin II receptor type 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Postsynaptic Density
Apical Plasma Membrane
Dendritic Spine
Dendritic Shaft
Cell Body
Postsynaptic Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Microtubule Binding
Angiotensin Type I Receptor Activity
G Protein-coupled Receptor Activity
Angiotensin Type II Receptor Activity
Protein Binding
Bradykinin Receptor Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Macroautophagy
Mitotic Cell Cycle Phase Transition
Regulation Of Synaptic Plasticity
Regulation Of Dendrite Morphogenesis
Regulation Of Cell Growth
Kidney Development
Renin-angiotensin Regulation Of Aldosterone Production
Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Rho Protein Signal Transduction
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Cholesterol Esterification
Regulation Of Vasoconstriction
Calcium-mediated Signaling
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phospholipase A2 Activity
Positive Regulation Of NAD(P)H Oxidase Activity
Low-density Lipoprotein Particle Remodeling
Regulation Of Renal Sodium Excretion
Angiotensin-activated Signaling Pathway
Regulation Of Cell Population Proliferation
Regulation Of Inflammatory Response
Positive Regulation Of Inflammatory Response
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Cell Chemotaxis
Phospholipase C-activating Angiotensin-activated Signaling Pathway
Blood Vessel Diameter Maintenance
Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Peptide ligand-binding receptors
G alpha (q) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Drugs
Valsartan
Olmesartan
Losartan
Candesartan cilexetil
Eprosartan
Telmisartan
Irbesartan
Forasartan
Saprisartan
Tasosartan
CYT006-AngQb
Azilsartan medoxomil
Fimasartan
Angiotensin II
Candesartan
Diseases
Renal tubular dysgenesis
GWAS
Adult body size (
32376654
)
Circulating myeloperoxidase levels (serum) (
23620142
)
Dental caries (
23064961
23259602
)
Influenza A (H1N1) infection (
26379185
)
Major depressive disorder (broad) (
20038947
)
Preeclampsia (
23551011
)
Rheumatoid arthritis (
30891314
)
Severe influenza A (H1N1) infection (
26379185
)
Susceptibility to persistent hepatitis B virus infection (
27244555
)
Birth weight (
31043758
)
Chin dimples (
27182965
)
Height (
31562340
)
Lead levels in blood (
25820613
)
Monobrow (
27182965
)
Type 2 diabetes (
31049640
)
Interacting Genes
100 interacting genes:
AGTR1
AMOT
AP1M1
BYSL
CARD9
CCDC102B
CCDC120
CCDC13
CCDC187
CCDC57
CCHCR1
CDC23
CDC25C
CDC37
CDC7
CDK1
CEP83
CKS1B
COG2
COPB1
CWF19L2
DDX6
EEF1G
ELOA
ENKD1
EXOC8
FAM161A
FAM161B
FAM50B
FAM71F1
FAM81B
FAM90A1
GAS8
GOLGA1
GPKOW
HMGB2
IDO2
KANK2
KAT5
KAZN
KDM1A
KIF9
KIFC3
LENG1
LMNB2
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAPK9
MCRS1
METTL21A
MFAP1
MID2
NEK6
NTAQ1
PIBF1
PICK1
PLEKHA7
POLR1C
POLR3C
PPP1R18
PRKAB2
PRPF18
PRPF3
PSMA1
PSPC1
QARS1
RABIF
RHPN1
RSPH14
RUNX1T1
SCNM1
SGF29
SOGA1
SPDYC
SUFU
SYT17
SYT6
SYTL4
TBC1D1
TBC1D7
TCEA2
TSGA10
TSGA10IP
TTC9C
TXLNA
TXLNB
TXNDC9
UBASH3A
ZGPAT
ZMYND19
ZNF250
ZNF3
ZNF35
ZNF417
ZNF572
ZNF587
76 interacting genes:
ABI3
ADD3
AGT
AGTRAP
AP2M1
ARFGAP1
ARHGDIG
ARRB1
ARRB2
ATP13A1
ATP1B1
BAALC
BASP1
BDKRB2
BNIP3
BRD8
CBR1
CCDC25
CD37
CERS6
CUEDC2
DBNDD2
DNAJC14
DNAJC8
EGFR
FAM13B
FBXW11
FNBP1
GHITM
GNA12
GOT1
GPAA1
GPRASP1
GRK2
GRK3
GRK5
HDGFL2
HHATL
HRAS
JAK1
JAK2
JKAMP
KIAA0930
LCNL1
LLGL1
LZTS1
NACAD
NDRG2
NOS3
NPTN
NUP88
OAZ1
PCMT1
PDE6H
PLCG1
PLCH2
PNMA1
PPP1R3F
PSMD10
PTGFR
RAB5A
RAF1
RBSN
RTN3
SAE1
SCG5
SELENOF
SERINC3
SLC16A1
SPG21
THOP1
TMEM161A
TMEM80
UBR4
UGT8
YWHAQ
Entrez ID
11178
185
HPRD ID
05945
00107
Ensembl ID
ENSG00000061337
ENSG00000144891
Uniprot IDs
Q9Y250
A0A0A0MSE3
D3DNG8
P30556
Q53YY0
Q6NUP5
PDB IDs
1ZV0
4YAY
4ZUD
6DO1
6OS0
6OS1
6OS2
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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