LZTS1 and COG2

Data Source:
BioGRID (two hybrid)

		LZTS1	COG2
Description		leucine zipper tumor suppressor 1	component of oligomeric golgi complex 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Postsynaptic Density Apical Plasma Membrane Dendritic Spine Dendritic Shaft Cell Body Postsynaptic Membrane	Golgi Membrane Golgi Stack Cytosol Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Macroautophagy Mitotic Cell Cycle Phase Transition Regulation Of Synaptic Plasticity Regulation Of Dendrite Morphogenesis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi Organization Protein Transport
Pathways			COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Adult body size ( 32376654) Circulating myeloperoxidase levels (serum) ( 23620142) Dental caries ( 23064961 23259602) Influenza A (H1N1) infection ( 26379185) Major depressive disorder (broad) ( 20038947) Preeclampsia ( 23551011) Rheumatoid arthritis ( 30891314) Severe influenza A (H1N1) infection ( 26379185) Susceptibility to persistent hepatitis B virus infection ( 27244555)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		100 interacting genes: AGTR1 AMOT AP1M1 BYSL CARD9 CCDC102B CCDC120 CCDC13 CCDC187 CCDC57 CCHCR1 CDC23 CDC25C CDC37 CDC7 CDK1 CEP83 CKS1B COG2 COPB1 CWF19L2 DDX6 EEF1G ELOA ENKD1 EXOC8 FAM161A FAM161B FAM50B FAM71F1 FAM81B FAM90A1 GAS8 GOLGA1 GPKOW HMGB2 IDO2 KANK2 KAT5 KAZN KDM1A KIF9 KIFC3 LENG1 LMNB2 LMO1 LMO2 LMO3 LMO4 LNX1 LSM2 MAPK9 MCRS1 METTL21A MFAP1 MID2 NEK6 NTAQ1 PIBF1 PICK1 PLEKHA7 POLR1C POLR3C PPP1R18 PRKAB2 PRPF18 PRPF3 PSMA1 PSPC1 QARS1 RABIF RHPN1 RSPH14 RUNX1T1 SCNM1 SGF29 SOGA1 SPDYC SUFU SYT17 SYT6 SYTL4 TBC1D1 TBC1D7 TCEA2 TSGA10 TSGA10IP TTC9C TXLNA TXLNB TXNDC9 UBASH3A ZGPAT ZMYND19 ZNF250 ZNF3 ZNF35 ZNF417 ZNF572 ZNF587	7 interacting genes: CEP68 COG3 COG4 FBXL17 LENG8 LZTS1 MTUS2
Entrez ID		11178	22796
HPRD ID		05945	07372
Ensembl ID		ENSG00000061337	ENSG00000135775
Uniprot IDs		Q9Y250	B1ALW7 Q14746
PDB IDs
Enriched GO Terms of Interacting Partners?
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