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LZTS1 and HMGB2
Data Source:
BioGRID
(two hybrid)
LZTS1
HMGB2
Description
leucine zipper tumor suppressor 1
high mobility group box 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Postsynaptic Density
Apical Plasma Membrane
Dendritic Spine
Dendritic Shaft
Cell Body
Postsynaptic Membrane
Chromatin
Condensed Chromosome
Extracellular Space
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Microtubule Binding
Four-way Junction DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
Damaged DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
Transcription Factor Binding
DNA Binding, Bending
Protein Domain Specific Binding
Chemoattractant Activity
Non-sequence-specific DNA Binding, Bending
RAGE Receptor Binding
Supercoiled DNA Binding
Biological Process
Negative Regulation Of Macroautophagy
Mitotic Cell Cycle Phase Transition
Regulation Of Synaptic Plasticity
Regulation Of Dendrite Morphogenesis
Positive Regulation Of Endothelial Cell Proliferation
Inflammatory Response To Antigenic Stimulus
DNA Topological Change
Double-strand Break Repair Via Nonhomologous End Joining
Apoptotic DNA Fragmentation
Chromatin Organization
Nucleosome Assembly
Regulation Of Transcription By RNA Polymerase II
Spermatid Nucleus Differentiation
Male Gonad Development
Positive Regulation Of Nuclease Activity
DNA Geometric Change
Response To Lipopolysaccharide
Positive Regulation Of Interferon-beta Production
V(D)J Recombination
Positive Regulation Of DNA Binding
Innate Immune Response
Positive Regulation Of Innate Immune Response
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Response To Steroid Hormone
Regulation Of Neurogenesis
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Chemotaxis
Cell Chemotaxis
Cellular Response To Lipopolysaccharide
Regulation Of Stem Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Circulating myeloperoxidase levels (serum) (
23620142
)
Dental caries (
23064961
23259602
)
Influenza A (H1N1) infection (
26379185
)
Major depressive disorder (broad) (
20038947
)
Preeclampsia (
23551011
)
Rheumatoid arthritis (
30891314
)
Severe influenza A (H1N1) infection (
26379185
)
Susceptibility to persistent hepatitis B virus infection (
27244555
)
Interacting Genes
100 interacting genes:
AGTR1
AMOT
AP1M1
BYSL
CARD9
CCDC102B
CCDC120
CCDC13
CCDC187
CCDC57
CCHCR1
CDC23
CDC25C
CDC37
CDC7
CDK1
CEP83
CKS1B
COG2
COPB1
CWF19L2
DDX6
EEF1G
ELOA
ENKD1
EXOC8
FAM161A
FAM161B
FAM50B
FAM71F1
FAM81B
FAM90A1
GAS8
GOLGA1
GPKOW
HMGB2
IDO2
KANK2
KAT5
KAZN
KDM1A
KIF9
KIFC3
LENG1
LMNB2
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAPK9
MCRS1
METTL21A
MFAP1
MID2
NEK6
NTAQ1
PIBF1
PICK1
PLEKHA7
POLR1C
POLR3C
PPP1R18
PRKAB2
PRPF18
PRPF3
PSMA1
PSPC1
QARS1
RABIF
RHPN1
RSPH14
RUNX1T1
SCNM1
SGF29
SOGA1
SPDYC
SUFU
SYT17
SYT6
SYTL4
TBC1D1
TBC1D7
TCEA2
TSGA10
TSGA10IP
TTC9C
TXLNA
TXLNB
TXNDC9
UBASH3A
ZGPAT
ZMYND19
ZNF250
ZNF3
ZNF35
ZNF417
ZNF572
ZNF587
38 interacting genes:
APEX1
APP
AR
ARCN1
C1QBP
CACTIN
CHAF1A
CREBBP
CSNK1A1
EIF1
FBXO7
GZMA
GZMK
H3-3A
HACD3
HDLBP
HMGA1
LZTS1
MIEN1
NAP1L1
NCBP3
NEXN
NR3C1
PGR
PKNOX1
POU2F1
POU2F2
POU3F1
POU5F1
PRKDC
RAG1
SAMM50
SET
TP53
TSNAX
ZNF428
ZNF622
ZNF668
Entrez ID
11178
3148
HPRD ID
05945
01229
Ensembl ID
ENSG00000061337
ENSG00000164104
Uniprot IDs
Q9Y250
P26583
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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