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AP3S2 and E2F4
Data Source:
BioGRID
(two hybrid)
AP3S2
E2F4
Description
adaptor related protein complex 3 subunit sigma 2
E2F transcription factor 4
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
AP-3 Adaptor Complex
Cytoplasmic Vesicle Membrane
Intracellular Membrane-bounded Organelle
Axon Cytoplasm
Chromatin
Nucleoplasm
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Intracellular Protein Transport
Anterograde Axonal Transport
Vesicle-mediated Transport
Anterograde Synaptic Vesicle Transport
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Epithelial Cell Development
Regulation Of Transcription By RNA Polymerase II
Cell Volume Homeostasis
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Blood Circulation
Animal Organ Morphogenesis
Regulation Of Cell Population Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Centriole Assembly
Multi-ciliated Epithelial Cell Differentiation
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS
Type 2 diabetes (
24509480
30054458
21874001
29358691
30297969
23945395
32499647
30718926
28869590
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
7 interacting genes:
AP3B1
AP3D1
AP3S1
ARF1
ARF6
E2F4
SCARB2
31 interacting genes:
AP3S2
ARID3A
ATAD2
BRCA1
CHMP2A
CHUK
FHL2
HCFC1
ID3
IKBKB
KAT5
LRRK2
MFHAS1
MGA
NDN
NOLC1
PCM1
PIN1
POLR1D
RB1
RBL1
RBL2
RNF144A
RYBP
SMAD2
SMAD3
SPIB
TFDP1
TFDP2
TRRAP
XPO1
Entrez ID
10239
1874
HPRD ID
03880
02806
Ensembl ID
ENSG00000157823
ENSG00000205250
Uniprot IDs
A0A024RC62
P59780
Q16254
PDB IDs
1CF7
5TUU
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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