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E2F4 and CHMP2A
Data Source:
BioGRID
(two hybrid)
E2F4
CHMP2A
Description
E2F transcription factor 4
charged multivesicular body protein 2A
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleoplasm
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Chromatin
ESCRT III Complex
Nuclear Envelope
Multivesicular Body
Cytosol
Membrane
Membrane Coat
Late Endosome Membrane
Extracellular Exosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Protein Binding
Protein Domain Specific Binding
Phosphatidylcholine Binding
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Epithelial Cell Development
Regulation Of Transcription By RNA Polymerase II
Cell Volume Homeostasis
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Blood Circulation
Animal Organ Morphogenesis
Regulation Of Cell Population Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Centriole Assembly
Multi-ciliated Epithelial Cell Differentiation
Nucleus Organization
Mitotic Metaphase Plate Congression
Membrane Invagination
Exit From Mitosis
Regulation Of Centrosome Duplication
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Nuclear Envelope Reassembly
Endosome Transport Via Multivesicular Body Sorting Pathway
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Establishment Of Protein Localization
Late Endosome To Vacuole Transport
Regulation Of Viral Process
Protein Polymerization
Protein Homooligomerization
Negative Regulation Of Cell Death
Midbody Abscission
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Negative Regulation Of Centriole Elongation
ESCRT III Complex Disassembly
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
Budding and maturation of HIV virion
Macroautophagy
Lysosome Vesicle Biogenesis
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Sealing of the nuclear envelope (NE) by ESCRT-III
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Interacting Genes
31 interacting genes:
AP3S2
ARID3A
ATAD2
BRCA1
CHMP2A
CHUK
FHL2
HCFC1
ID3
IKBKB
KAT5
LRRK2
MFHAS1
MGA
NDN
NOLC1
PCM1
PIN1
POLR1D
RB1
RBL1
RBL2
RNF144A
RYBP
SMAD2
SMAD3
SPIB
TFDP1
TFDP2
TRRAP
XPO1
13 interacting genes:
CHMP3
DOCK8
E2F4
EIF2B5
MITD1
NOL4
STAMBP
TGFB3
UFD1
USP54
USP8
VPS4A
VPS4B
Entrez ID
1874
27243
HPRD ID
02806
12520
Ensembl ID
ENSG00000205250
ENSG00000130724
Uniprot IDs
Q16254
A0A024R4S0
O43633
PDB IDs
1CF7
5TUU
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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