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E2F4 and ATAD2
Data Source:
BioGRID
(affinity chromatography technology, pull down)
E2F4
ATAD2
Description
E2F transcription factor 4
ATPase family AAA domain containing 2
Image
GO Annotations
Cellular Component
Chromatin
Nucleoplasm
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Nucleus
Nucleoplasm
Extracellular Exosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Chromatin Binding
Protein Binding
ATP Binding
ATPase Activity
Histone Binding
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Epithelial Cell Development
Regulation Of Transcription By RNA Polymerase II
Cell Volume Homeostasis
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Blood Circulation
Animal Organ Morphogenesis
Regulation Of Cell Population Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Centriole Assembly
Multi-ciliated Epithelial Cell Differentiation
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Chromatin Silencing
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
31 interacting genes:
AP3S2
ARID3A
ATAD2
BRCA1
CHMP2A
CHUK
FHL2
HCFC1
ID3
IKBKB
KAT5
LRRK2
MFHAS1
MGA
NDN
NOLC1
PCM1
PIN1
POLR1D
RB1
RBL1
RBL2
RNF144A
RYBP
SMAD2
SMAD3
SPIB
TFDP1
TFDP2
TRRAP
XPO1
12 interacting genes:
BAG4
BCAR3
CASP8
E2F1
E2F2
E2F3
E2F4
ESR1
H3-4
H4C14
MYC
NCOA3
Entrez ID
1874
29028
HPRD ID
02806
10678
Ensembl ID
ENSG00000205250
ENSG00000156802
Uniprot IDs
Q16254
A0A024R9G7
Q6PL18
PDB IDs
1CF7
5TUU
3DAI
4QSP
4QSQ
4QSR
4QSS
4QST
4QSU
4QSV
4QSW
4QSX
4QUT
4QUU
4TT2
4TT4
4TT6
4TTE
4TU4
4TU6
4TYL
4TZ2
4TZ8
5A5N
5A5O
5A5P
5A5Q
5A5R
5A81
5A82
5A83
5EPB
5F36
5F3A
5LJ0
5QXI
5QXJ
5QXK
5QXL
5QXM
5QXN
5QXO
5QXP
5QXQ
5QXR
5QXS
5QXT
5QXU
5QXV
5QXW
5QXX
5QXY
5QXZ
5QY0
5R4E
5R4F
5R4V
5R4W
5R4X
5R4Y
5R4Z
6CPS
6EPJ
6EPR
6EPS
6EPT
6EPU
6EPV
6EPW
6EPX
6HDN
6HDO
6HI3
6HI4
6HI5
6HI6
6HI7
6HI8
6HIA
6HIB
6HIC
6HID
6HIE
6S55
6S56
6S57
6YB4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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