AP3S2 and AP3B1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		AP3S2	AP3B1
Description		adaptor related protein complex 3 subunit sigma 2	adaptor related protein complex 3 subunit beta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus AP-3 Adaptor Complex Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Axon Cytoplasm	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm
	Molecular Function		Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding
	Biological Process	Intracellular Protein Transport Anterograde Axonal Transport Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development
Pathways			Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions
Drugs
Diseases			Hermansky-Pudlak syndrome (HPS)
GWAS		Type 2 diabetes ( 24509480 30054458 21874001 29358691 30297969 23945395 32499647 30718926 28869590)	Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)
Interacting Genes		7 interacting genes: AP3B1 AP3D1 AP3S1 ARF1 ARF6 E2F4 SCARB2	14 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 GKAP1 SLC30A3
Entrez ID		10239	8546
HPRD ID		03880	04551
Ensembl ID		ENSG00000157823	ENSG00000132842
Uniprot IDs		A0A024RC62 P59780	A0A0S2Z5J4 O00203
PDB IDs
Enriched GO Terms of Interacting Partners?
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