Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
H1-1 and GZMA
Data Source:
BioGRID
(enzymatic study)
H1-1
GZMA
Description
H1.1 linker histone, cluster member
granzyme A
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleosome
Euchromatin
Nucleus
Nucleoplasm
Immunological Synapse
Extracellular Region
Nucleus
Molecular Function
Double-stranded DNA Binding
Protein Binding
Chromatin DNA Binding
Nucleosomal DNA Binding
Serine-type Endopeptidase Activity
Protein Binding
Protein Homodimerization Activity
Biological Process
Nucleosome Assembly
Spermatogenesis
Nucleosome Positioning
Chromosome Condensation
Negative Regulation Of Chromatin Silencing
Negative Regulation Of DNA Recombination
Apoptotic Process
Immune Response
Response To Bacterium
Cytolysis
Negative Regulation Of Endodeoxyribonuclease Activity
Positive Regulation Of Apoptotic Process
Negative Regulation Of DNA Binding
Negative Regulation Of Oxidoreductase Activity
Proteolysis Involved In Cellular Protein Catabolic Process
Pyroptosis
Granzyme-mediated Programmed Cell Death Signaling Pathway
Cytotoxic T Cell Pyroptotic Process
Pathways
Apoptosis induced DNA fragmentation
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes
52 interacting genes:
AEBP2
APP
CCNA1
CCNA2
CCNB1
CCND2
CCNE1
CDK1
CDK2
CDK4
CDK5
CDK6
CDK7
CDKN1B
CRP
CTCFL
EED
EHMT2
EP300
EZH2
GADD45A
GZMA
IRAK4
KAT2B
LIMK1
LIMK2
LOX
NAP1L1
NAP1L4
NASP
NSD3
PAK4
PARP1
PARP3
PELP1
PRDM1
PRKCA
PRKCB
PRKCD
PRKCE
PRKCZ
PRKDC
PTMA
RBBP4
RPS6KA5
SET
SNCA
SUZ12
TAF1
TERF1
TERF2IP
TLK1
17 interacting genes:
ACTG1
APEX1
GOLGA2
H1-1
H2BC21
HDC
HMGB2
HNRNPK
HSP90AA1
HSPA4
LMNA
LMNB1
NCL
NDUFS3
SET
XRCC5
XRCC6
Entrez ID
3024
3001
HPRD ID
00820
00771
Ensembl ID
ENSG00000124610
ENSG00000145649
Uniprot IDs
Q02539
P12544
PDB IDs
1HF1
1OP8
1ORF
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?