ANKLE2 and ZFYVE9

Data Source:
BioGRID (two hybrid)

		ANKLE2	ZFYVE9
Description		ankyrin repeat and LEM domain containing 2	zinc finger FYVE-type containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Mitotic Nuclear Envelope Reassembly Central Nervous System Development Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Phosphorylation Negative Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Catalytic Activity Cell Division	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways		Initiation of Nuclear Envelope (NE) Reformation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Immune response to smallpox vaccine (IL-6) ( 22542470) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: MAPK13 ZFYVE9 ZNF512B	38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		23141	9372
HPRD ID		19309	04782
Ensembl ID		ENSG00000176915	ENSG00000157077
Uniprot IDs		Q86XL3	O95405
PDB IDs			1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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