ANKLE2 and MAPK13

Data Source:
BioGRID (two hybrid)

		ANKLE2	MAPK13
Description		ankyrin repeat and LEM domain containing 2	mitogen-activated protein kinase 13
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding
	Biological Process	Mitotic Nuclear Envelope Reassembly Central Nervous System Development Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Phosphorylation Negative Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Catalytic Activity Cell Division	Response To Osmotic Stress Cell Cycle Peptidyl-serine Phosphorylation Positive Regulation Of Interleukin-6 Production Cellular Response To UV Intracellular Signal Transduction Positive Regulation Of Inflammatory Response Stress-activated MAPK Cascade Cellular Response To Hydrogen Peroxide Cellular Response To Interleukin-1 Cellular Response To Sorbitol Cellular Response To Anisomycin Cellular Response To Sodium Arsenite
Pathways		Initiation of Nuclear Envelope (NE) Reformation	NOD1/2 Signaling Pathway p38MAPK events DSCAM interactions VEGFA-VEGFR2 Pathway
Drugs			Minocycline KC706 Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Immune response to smallpox vaccine (IL-6) ( 22542470) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Refractive error ( 32231278)	Birth weight ( 31043758) Blood protein levels ( 30072576 29875488) Offspring birth weight ( 31043758)
Interacting Genes		3 interacting genes: MAPK13 ZFYVE9 ZNF512B	16 interacting genes: AKIP1 ANKLE2 APP ATF2 EEF2K FGF12 GPX4 HTRA2 MAP2K6 MAP3K4 MAPKAPK3 MAPKAPK5 MAPT MBP SMAD4 SQSTM1
Entrez ID		23141	5603
HPRD ID		19309	09113
Ensembl ID		ENSG00000176915	ENSG00000156711
Uniprot IDs		Q86XL3	A0A024RD04 O15264
PDB IDs			3COI 4EYJ 4EYM 4MYG 4YNO 5EKN 5EKO
Enriched GO Terms of Interacting Partners?
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