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TAF1A and JMJD6
Data Source:
BioGRID
(two hybrid)
TAF1A
JMJD6
Description
TATA-box binding protein associated factor, RNA polymerase I subunit A
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
Image
No pdb structure
GO Annotations
Cellular Component
RNA Polymerase I Transcription Regulator Complex
Nucleoplasm
Microtubule Cytoskeleton
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Ribonucleoprotein Complex
Molecular Function
DNA Binding
Protein Binding
RNA Binding
Single-stranded RNA Binding
Iron Ion Binding
Protein Binding
Demethylase Activity
Histone Demethylase Activity
Histone Demethylase Activity (H3-R2 Specific)
Histone Demethylase Activity (H4-R3 Specific)
Oxidative RNA Demethylase Activity
Signaling Receptor Activity
Identical Protein Binding
Peptidyl-lysine 5-dioxygenase Activity
P-TEFb Complex Binding
Transcription Regulator Activator Activity
Biological Process
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Kidney Development
Sprouting Angiogenesis
MRNA Processing
Protein Demethylation
Cell Surface Receptor Signaling Pathway
Heart Development
RNA Splicing
Protein Phosphopantetheinylation
Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine
Lung Development
T Cell Differentiation In Thymus
Oxidative RNA Demethylation
Macrophage Activation
Recognition Of Apoptotic Cell
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of MRNA Splicing, Via Spliceosome
Erythrocyte Development
Protein Homooligomerization
Retina Development In Camera-type Eye
Histone H3-R2 Demethylation
Histone H4-R3 Demethylation
Pathways
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
HDMs demethylate histones
Drugs
Diseases
GWAS
Trunk fat mass (
28552196
)
Neutrophil count (
32888494
)
Retinal arteriolar caliber (
23776548
)
Interacting Genes
20 interacting genes:
ANP32A
ESR1
H2AC20
H2BC21
H3-4
H3C1
H4-16
H4C1
JMJD6
NKAPD1
POLR1G
RRN3
RUNX2
SET
TAF12
TAF1B
TAF1C
TBP
TP53
UBTF
27 interacting genes:
AEBP2
ANKEF1
C17orf97
CCNL1
CENPL
CXCL14
DIP2A
FGD5
FRMD6
GNA14
H2BC11
H3C1
H4C1
HMGXB4
LARP7
NAA50
NFIX
NHP2
PRPF38A
PSMC1
RSPO2
SLFN12
SLU7
STAC3
TAF1A
U2AF1
ZNF451
Entrez ID
9015
23210
HPRD ID
05362
05371
Ensembl ID
ENSG00000143498
ENSG00000070495
Uniprot IDs
A8K4K5
B4DS21
Q15573
Q6NYC1
PDB IDs
3K2O
3LD8
3LDB
6BNH
6GDY
6MEV
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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