TAF1A and TAF12

Data Source:
BioGRID (pull down)

		TAF1A	TAF12
Description		TATA-box binding protein associated factor, RNA polymerase I subunit A	TATA-box binding protein associated factor 12
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleoplasm Microtubule Cytoskeleton	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex
	Molecular Function	DNA Binding Protein Binding	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Positive Regulation Of Gene Expression, Epigenetic	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Trunk fat mass ( 28552196)	Type 2 diabetes ( 31049640)
Interacting Genes		20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4-16 H4C1 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF	23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		9015	6883
HPRD ID		05362	15981
Ensembl ID		ENSG00000143498	ENSG00000120656
Uniprot IDs		A8K4K5 B4DS21 Q15573	Q16514
PDB IDs			1H3O 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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