CGGBP1 and SUV39H2

Data Source:
HPRD (two hybrid)

		CGGBP1	SUV39H2
Description		CGG triplet repeat binding protein 1	suppressor of variegation 3-9 homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Double-stranded DNA Binding Protein Binding Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression DsDNA Loop Formation	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hand grip strength ( 29691431) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Red blood cell count ( 32888494)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		19 interacting genes: BOLA2 BOLA2B CDC37 CDKN2D FAM124A GLRX3 GORASP2 MRM1 NTAQ1 PAX6 PIAS2 PICK1 PLEKHF2 POLR1C REL SDCBP SUV39H2 TXN2 UBE3A	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		8545	79723
HPRD ID		04529	07580
Ensembl ID		ENSG00000163320	ENSG00000152455
Uniprot IDs		Q9UFW8	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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