VPS25 and TADA2A

Data Source:
BioGRID (two hybrid)

		VPS25	TADA2A
Description		vacuolar protein sorting 25 homolog	transcriptional adaptor 2A
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GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome	PCAF Complex Nucleus Chromosome SAGA-type Complex
	Molecular Function	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	HATs acetylate histones
Drugs
Diseases
GWAS			Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)
Interacting Genes		21 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 VPS36	48 interacting genes: ARNT2 C1orf109 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688
Entrez ID		84313	6871
HPRD ID		14396	03784
Ensembl ID		ENSG00000131475	ENSG00000276234
Uniprot IDs		A0A024R1X3 Q9BRG1	A0A024R0Y4 A0A087WWR4 B3KU13 O75478
PDB IDs		2ZME 3CUQ 3HTU	1X41
Enriched GO Terms of Interacting Partners?
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