VPS25 and CRLF3

Data Source:
BioGRID (two hybrid)

		VPS25	CRLF3
Description		vacuolar protein sorting 25 homolog	cytokine receptor like factor 3
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Cycle Arrest
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Birth weight ( 27680694) Chronic obstructive pulmonary disease ( 30804561) Height ( 28552196 18391951) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 29403010) Platelet distribution width ( 32888494)
Interacting Genes		21 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 VPS36	10 interacting genes: APPL2 DDIT4L KCTD21 KDM1A L3MBTL3 LGALS14 MYOZ3 RBM14 VPS25 ZFP1
Entrez ID		84313	51379
HPRD ID		14396	16757
Ensembl ID		ENSG00000131475	ENSG00000176390
Uniprot IDs		A0A024R1X3 Q9BRG1	Q8IUI8
PDB IDs		2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?
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