TADA2A and EIF4E2

Data Source:
BioGRID (two hybrid)

		TADA2A	EIF4E2
Description		transcriptional adaptor 2A	eukaryotic translation initiation factor 4E family member 2
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GO Annotations	Cellular Component	PCAF Complex Nucleus Chromosome SAGA-type Complex	P-body Cytoplasm Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated	Translational Initiation Negative Regulation Of Translation Gene Silencing By RNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation
Pathways		HATs acetylate histones	ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)
Interacting Genes		48 interacting genes: ARNT2 C1orf109 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688	45 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CARD9 CBY2 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MYOG NECAB2 NOTCH2NLA PRDM14 REL SPAG5 SPRY2 TADA2A TCF4 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		6871	9470
HPRD ID		03784	05798
Ensembl ID		ENSG00000276234	ENSG00000135930
Uniprot IDs		A0A024R0Y4 A0A087WWR4 B3KU13 O75478	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs		1X41	2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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