TADA2A and KLC4

Data Source:
BioGRID (two hybrid)

		TADA2A	KLC4
Description		transcriptional adaptor 2A	kinesin light chain 4
Image			No pdb structure
GO Annotations	Cellular Component	PCAF Complex Nucleus Chromosome SAGA-type Complex	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	Protein Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)	Hemoglobin levels ( 32327693)
Interacting Genes		48 interacting genes: ARNT2 C1orf109 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688	32 interacting genes: ABI3 AKAP9 APP CASK CEP57 CEP57L1 COIL DDX6 KATNAL1 KLC2 KPNA2 KRT13 KRT15 KRT16 KRT31 KRT33B KRT34 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SERTAD1 SLC16A9 TADA2A USHBP1 YWHAE YWHAZ ZNF343
Entrez ID		6871	89953
HPRD ID		03784	13932
Ensembl ID		ENSG00000276234	ENSG00000137171
Uniprot IDs		A0A024R0Y4 A0A087WWR4 B3KU13 O75478	A0A024RCZ8 Q9NSK0
PDB IDs		1X41
Enriched GO Terms of Interacting Partners?
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