VPS25 and B9D2

Data Source:
BioGRID (two hybrid)

		VPS25	B9D2
Description		vacuolar protein sorting 25 homolog	B9 domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome	Nucleus Centrosome Cytosol Membrane MKS Complex Ciliary Basal Body
	Molecular Function	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 32469254 29212778) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		21 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 VPS36	8 interacting genes: ALKBH7 P4HA3 PLEKHA7 PPP1R32 QARS1 SPAG8 TLX3 VPS25
Entrez ID		84313	80776
HPRD ID		14396	14613
Ensembl ID		ENSG00000131475	ENSG00000123810
Uniprot IDs		A0A024R1X3 Q9BRG1	Q9BPU9
PDB IDs		2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?
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