Description |
tripartite motif containing 8 |
X-linked inhibitor of apoptosis |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Body mass index ( 28448500)
- Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
- Body mass index in physically active individuals ( 28448500)
- Brain morphology (MOSTest) ( 32665545)
- Feeling nervous ( 29500382)
- Prostate cancer ( 23535732)
- Pulse pressure ( 30578418)
- Refractive error ( 32231278)
- Schizophrenia ( 25056061 30285260)
- Smoking status (ever vs never smokers) ( 30643258)
- Ulcerative colitis ( 26192919)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
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Interacting Genes |
63 interacting genes:
BRAP
CATSPER1
CBL
CCNH
DCUN1D1
FAM124B
HOXA1
ITSN1
LNX1
LONRF1
MAGEC2
MKRN3
MSL2
MTURN
NUDT10
OTUB2
PCGF5
RAD18
RAD23A
RC3H2
RCHY1
RNF111
RNF113A
RNF138
RNF141
RNF168
RNF181
RNF41
RNF7
SIAH1
SOCS1
TICAM1
TNFAIP3
TNIP3
TNPO2
TNS2
TRAF5
TRIM15
TRIM2
TRIM21
TRIM24
TRIM25
TRIM39
TRIM43
TRIM47
TRIM9
UBASH3A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2L6
UBE2V1
UBE2W
UBXN7
UHRF2
USP2
USP21
USP39
USP5
USP7
XIAP
YOD1
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92 interacting genes:
ACVRL1
AFP
AIFM1
AKT1
AKT2
BCL2
BIRC5
BOLA1
BOLA2
BOLA2B
BRCA1
CASP10
CASP3
CASP7
CASP9
CCNB1
CDC42
CDK1
CHEK1
CKS1B
COMMD1
DIABLO
DNM2
DTX3
DYNLL2
ELAVL1
ERCC3
FAF1
GCC1
GOLGA2
GSK3B
GSPT1
HNRNPA1
HSPA1A
HTRA1
HTRA2
IKBKE
INPP5D
KCNJ6
LONRF1
MAGED1
MAP3K2
MAP3K3
MAP3K7
MCRS1
MDM2
NEK6
NOD1
NOD2
NOTCH1
NTAQ1
PIBF1
PPIH
PPM1K
QARS1
RAF1
RFC5
RIPK2
RIPK3
RIPK4
RUNX1T1
SEPTIN4
SERTAD1
SQSTM1
SSX2IP
STRADB
STUB1
TAB1
TAB2
TBK1
TGFBR1
TLE3
TRAF6
TRIM32
TRIM8
TTC23
UBB
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2I
UBE2J2
UBE2N
UBE2V1
UBE2V2
UBE2W
VPS37C
XAF1
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Entrez ID |
81603 |
331 |
HPRD ID |
06934 |
02094 |
Ensembl ID |
ENSG00000171206
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ENSG00000101966
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Uniprot IDs |
Q9BZR9
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B2R9R2
P98170
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PDB IDs |
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1C9Q
1F9X
1G3F
1G73
1I3O
1I4O
1I51
1KMC
1NW9
1TFQ
1TFT
2ECG
2JK7
2KNA
2OPY
2OPZ
2POI
2POP
2QRA
2VSL
3CLX
3CM2
3CM7
3EYL
3G76
3HL5
3UW4
3UW5
4EC4
4HY0
4IC2
4IC3
4J3Y
4J44
4J45
4J46
4J47
4J48
4KJU
4KJV
4KMP
4MTZ
4OXC
4WVS
4WVT
4WVU
5C0K
5C0L
5C3H
5C3K
5C7A
5C7B
5C7C
5C7D
5C83
5C84
5M6E
5M6F
5M6H
5M6L
5M6M
5O6T
5OQW
6EY2
6GJW
6QCI
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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