MCM3AP and TAF1D

Data Source:
BioGRID (two hybrid)

		MCM3AP	TAF1D
Description		minichromosome maintenance complex component 3 associated protein	TATA-box binding protein associated factor, RNA polymerase I subunit D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Membrane Nuclear Pore Nuclear Basket Transcription Export Complex 2	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle
	Molecular Function	Nucleic Acid Binding Chromatin Binding Histone Acetyltransferase Activity Protein Binding H3 Histone Acetyltransferase Activity Histone Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Export From Nucleus Somatic Hypermutation Of Immunoglobulin Genes Poly(A)+ MRNA Export From Nucleus Nucleosome Organization Histone H3 Acetylation	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic
Pathways			SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Periodontitis ( 30218097) Testicular germ cell tumor ( 25877299 28604728 23666240)
Interacting Genes		19 interacting genes: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1	24 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TAF1B TMSB4X UBE2D1 UBTF
Entrez ID		8888	79101
HPRD ID		04483	14679
Ensembl ID		ENSG00000160294	ENSG00000166012
Uniprot IDs		O60318	A0A024R3A9 Q9H5J8
PDB IDs		4DHX
Enriched GO Terms of Interacting Partners?
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