POLR3F and GTF3C4

Data Source:
HPRD (in vivo, in vitro)

		POLR3F	GTF3C4
Description		RNA polymerase III subunit F	general transcription factor IIIC subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion
	Molecular Function	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	13 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F SUMO2 TBP
Entrez ID		10621	9329
HPRD ID		15156	11998
Ensembl ID		ENSG00000132664	ENSG00000125484
Uniprot IDs		Q05DB8 Q9H1D9	B3KNH2 Q9UKN8
PDB IDs		2DK5 2YU3
Enriched GO Terms of Interacting Partners?
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