DDX54 and PJA1

Data Source:
BioGRID (enzymatic study)

		DDX54	PJA1
Description		DEAD-box helicase 54	praja ring finger ubiquitin ligase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Golgi Apparatus Membrane	Cytoplasm
	Molecular Function	Transcription Corepressor Activity RNA Binding RNA Helicase Activity Signaling Receptor Binding ATP Binding Estrogen Receptor Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	RRNA Processing RNA Processing RNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated	Protein Ubiquitination Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Response to fenofibrate (adiponectin levels) ( 23149075)	Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		19 interacting genes: APP CASK CSNK2A1 DVL3 DYNLT1 ESR1 ESR2 NEDD4 NEDD4L NR3C1 PGR PJA1 POLR2G PTPRD SEMA4A SMURF1 TMED9 YWHAE ZNF394	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		79039	64219
HPRD ID		13129	02335
Ensembl ID		ENSG00000123064	ENSG00000181191
Uniprot IDs		Q8TDD1	Q8NG27
PDB IDs			2L0B
Enriched GO Terms of Interacting Partners?
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