DDX54 and SEMA4A

Data Source:
BioGRID (two hybrid)

		DDX54	SEMA4A
Description		DEAD-box helicase 54	semaphorin 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Golgi Apparatus Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Transcription Corepressor Activity RNA Binding RNA Helicase Activity Signaling Receptor Binding ATP Binding Estrogen Receptor Binding	Protein Binding Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	RRNA Processing RNA Processing RNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated	Angiogenesis Neural Crest Cell Migration Axon Guidance Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration T-helper 1 Cell Differentiation Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway Positive Regulation Of Excitatory Synapse Assembly Positive Regulation Of Inhibitory Synapse Assembly
Pathways			Other semaphorin interactions
Drugs
Diseases			Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS		Body mass index ( 26426971) Response to fenofibrate (adiponectin levels) ( 23149075)	Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Platelet count ( 32888494) Stroke ( 29531354) Systolic blood pressure ( 30224653)
Interacting Genes		19 interacting genes: APP CASK CSNK2A1 DVL3 DYNLT1 ESR1 ESR2 NEDD4 NEDD4L NR3C1 PGR PJA1 POLR2G PTPRD SEMA4A SMURF1 TMED9 YWHAE ZNF394	3 interacting genes: DDX54 HAVCR1 PLXND1
Entrez ID		79039	64218
HPRD ID		13129	09528
Ensembl ID		ENSG00000123064	ENSG00000196189
Uniprot IDs		Q8TDD1	B4DKS5 Q9H3S1
PDB IDs
Enriched GO Terms of Interacting Partners?
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