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VIM and TRIM14
Data Source:
BioGRID
(proximity labelling technology, two hybrid)
VIM
TRIM14
Description
vimentin
tripartite motif containing 14
Image
GO Annotations
Cellular Component
Cytoplasm
Peroxisome
Cytosol
Polysome
Cytoskeleton
Intermediate Filament
Plasma Membrane
Focal Adhesion
Nuclear Matrix
Cell Leading Edge
Neuron Projection
Intermediate Filament Cytoskeleton
Phagocytic Vesicle
Extracellular Exosome
Ribonucleoprotein Complex
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Cytosol
Phagocytic Vesicle
Molecular Function
Double-stranded RNA Binding
Structural Constituent Of Cytoskeleton
Structural Constituent Of Eye Lens
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Scaffold Protein Binding
Keratin Filament Binding
Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Neuron Projection Development
Astrocyte Development
Viral Process
Cytokine-mediated Signaling Pathway
Muscle Filament Sliding
Positive Regulation Of Collagen Biosynthetic Process
Regulation Of MRNA Stability
Intermediate Filament Organization
Positive Regulation Of Translation
Bergmann Glial Cell Differentiation
SMAD Protein Signal Transduction
Lens Fiber Cell Development
Cellular Response To Lipopolysaccharide
Cellular Response To Muramyl Dipeptide
Cellular Response To Interferon-gamma
Protein Polyubiquitination
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Regulation Of Protein Localization
Negative Regulation Of Viral Transcription
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Caspase-mediated cleavage of cytoskeletal proteins
Striated Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
Chaperone Mediated Autophagy
Late endosomal microautophagy
Aggrephagy
Interferon gamma signaling
Drugs
Artenimol
Phenethyl Isothiocyanate
Diseases
GWAS
Cholesterol, total (
24097068
)
HDL cholesterol levels (
32203549
)
Mean spheric corpuscular volume (
32888494
)
Total cholesterol levels (
28334899
)
Triglyceride levels (
32203549
)
Multiple sclerosis (
31604244
)
Interacting Genes
171 interacting genes:
ABLIM1
AKT1
ANKRD35
ANXA7
APIP
APLP1
APP
ARMC7
ARMCX2
ATN1
BFSP1
BHLHE40
BRD1
BYSL
C2CD6
CAMK2D
CAPN1
CASP3
CASP6
CASP7
CASP8
CASP9
CBX8
CCDC187
CDH5
CDK1
CDKN1A
CEP126
CHD3
COPS6
CRCT1
CREB1
CRMP1
CT55
CWF19L2
DCTN1
DEFB1
DES
DIS3L2
DNM1L
DPPA4
DSP
DUX4
DYNLL1
ENTR1
ESS2
FABP4
FAM107A
FAM118B
FAM161A
FUBP1
GADD45A
GEM
GFAP
GOPC
GRB2
GSK3B
HABP4
HAP1
HMG20B
HSPB1
HTRA2
ING5
IP6K1
ITGB4
IVNS1ABP
KARS1
KAT7
KIAA0408
KIF15
KIF9
KIFC3
KRT20
KRT75
LGALS14
LINC01554
LORICRIN
LRIF1
MAFG
MAN2A2
MCPH1
MEN1
MICAL1
MRPL44
MTDH
NEFL
NEFM
NFATC2
NFKBID
NIF3L1
NME2
NOC4L
NR1H2
NUP85
OSBP2
PAK2
PDLIM1
PIAS4
PKD1
PKN1
PKP1
PLA2G2A
PLA2G4A
PLEC
PNMA5
POLR1C
PPHLN1
PPL
PPP1R18
PRKACA
PRPH
PSMA1
PSMC5
PSMD7
PSME1
PUF60
RAB8B
RABAC1
RAD51
RBM48
RIBC2
ROCK1
RPA1
SCNM1
SERBP1
SETDB1
SH3GL1
SH3GL3
SH3YL1
SIRPA
SIRT6
SLC25A6
SLC27A6
SMAD3
SMARCB1
SRRT
STK19
STX1A
SUMO2
SUMO3
SYN1
TAB2
TCEA2
TCHP
TLE5
TNFRSF14
TNNT1
TRIM14
TRIM15
TRIM28
TRIM29
TRIOBP
TSC22D1
TTR
TUBA1C
TUBGCP4
TXLNB
TXN
TXN2
UPP1
UPP2
UROD
UTP14A
WBP11
XRCC4
YAE1
YWHAE
YWHAZ
ZHX1
ZNF384
ZNF572
84 interacting genes:
ABCF3
ADAMTS12
ALG13
AP3M1
ATP1B1
ATP1B3
ATP2A2
ATP5PB
ATP6V1H
BYSL
CARD9
CCDC125
CCDC57
CCDC6
CENPC
CIB3
CKS1B
CSPP1
EIF3G
ERCC3
ETFBKMT
EXOC8
FAM50B
FAT1
GOLGA2
GOLGA6L9
HERC3
HEXIM2
HNRNPF
IHO1
ITM2A
IVNS1ABP
KAT2B
KIF3A
KIFC3
LAMTOR1
LNX1
MAPRE3
MITD1
MNAT1
MRPL24
MYO15B
NCOR1
NDUFA9
NFAT5
NPC2
PCGF6
PDIA6
PHF11
PIM2
PLCG1
POLR1C
POLR2G
PPP2R3C
PRDM6
PRKAB2
PRPF31
PTPN21
RAB5A
RAB9A
RAD51D
RBM33
RLF
RNF125
RNF20
SLF2
SMARCB1
SMIM3
SPG21
STK38
TAX1BP1
TMEM167A
TRAF2
TSGA10
UBE2B
UBE2N
UNK
VIM
WDR35
WRNIP1
ZC4H2
ZFP36L2
ZGPAT
ZNF652
Entrez ID
7431
9830
HPRD ID
01899
05948
Ensembl ID
ENSG00000026025
ENSG00000106785
Uniprot IDs
P08670
V9HWE1
A0A024R165
Q14142
PDB IDs
1GK4
1GK6
1GK7
3G1E
3KLT
3S4R
3SSU
3SWK
3TRT
3UF1
4MCY
4MCZ
4MD0
4MD5
4MDI
4MDJ
4YPC
4YV3
5WHF
6ATF
6ATI
6BIR
6JBM
Enriched GO Terms of Interacting Partners
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