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TMPRSS2 and TMEM218
Data Source:
BioGRID
(two hybrid)
TMPRSS2
TMEM218
Description
transmembrane serine protease 2
transmembrane protein 218
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Extracellular Exosome
Cilium
Integral Component Of Membrane
Molecular Function
Serine-type Endopeptidase Activity
Scavenger Receptor Activity
Protein Binding
Serine-type Peptidase Activity
Protein Binding
Biological Process
Proteolysis
Endocytosis
Protein Autoprocessing
Positive Regulation Of Viral Entry Into Host Cell
Pathways
Attachment and Entry
Attachment and Entry
Attachment and Entry
Drugs
Camostat
Diseases
Prostate cancer
GWAS
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Prostate cancer (
25217961
)
Breast cancer (survival) (
25890600
)
Familial lung adenocarcinoma (
29924316
)
Interacting Genes
59 interacting genes:
ADIPOQ
ANKRD46
AQP1
BMP10
BNIP2
BNIP3
BRICD5
C1QL4
C2CD2L
C3orf52
CFHR5
CLEC7A
CLK1
CLN6
CMTM7
CNIH2
CNIH3
CTXN3
CXCL9
CYBC1
DEFB103A
DEFB103B
EDDM3B
ERG28
FAM3C
FAXDC2
IGFBP5
MOSPD3
NINJ2
PGAP2
PLLP
PLN
PLP1
PLP2
PTCH1
PTTG1IP
SCD
SEC22A
SELENOK
SFTPC
SLC35A1
SMIM1
STX7
STX8
TMEM11
TMEM120B
TMEM128
TMEM218
TMEM222
TMEM229B
TMEM243
TMEM60
TMEM79
TMEM86A
TMEM86B
TNF
UPK2
VAMP5
ZFPL1
72 interacting genes:
APH1A
AQP2
AQP6
ARL13B
ASZ1
ATP6V0E1
BSCL2
CD300A
CD53
CD79A
CLDN2
CLEC10A
CLEC17A
CPLX4
CREB3L1
CTLA4
DAGLA
EBP
ELOVL2
ELOVL4
EMP1
ERGIC3
FAM209A
FCER1G
FRMD3
GDAP1
GJB1
GJB4
GJB6
GPR152
GPR61
GPX8
IFNGR2
KCNJ6
KCNK5
KIR2DL3
LDLRAD1
LHFPL5
LMNA
LSMEM2
MFF
MS4A3
MTIF3
NPFFR2
PCNA
PDCD1LG2
PIK3IP1
PLEKHO1
PSCA
RETREG3
SAR1A
SDC3
SLC10A4
SLC10A6
SLC18A1
SMIM3
SSMEM1
TM4SF18
TMED8
TMEM106C
TMEM182
TMEM207
TMEM234
TMEM31
TMEM45B
TMEM52B
TMEM88
TMPRSS2
TRHR
TSPAN12
TSPAN18
VSIR
Entrez ID
7113
219854
HPRD ID
03637
19054
Ensembl ID
ENSG00000184012
ENSG00000150433
Uniprot IDs
O15393
A2RU14
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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