TMEM218 and TRHR

Data Source:
BioGRID (two hybrid)

		TMEM218	TRHR
Description		transmembrane protein 218	thyrotropin releasing hormone receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Thyrotropin-releasing Hormone Receptor Activity Protein Binding
	Biological Process		G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Protirelin
Diseases
GWAS		Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)	Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)
Interacting Genes		72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR	19 interacting genes: ARRB1 C1QL4 COMT EFNA5 FAM241B FXYD6-FXYD2 GJB2 IER3IP1 NIPAL4 PEDS1-UBE2V1 SLC39A2 SLC39A9 SLC41A1 TMEFF2 TMEM218 TMEM239 TRH UBE2J1 YIPF6
Entrez ID		219854	7201
HPRD ID		19054	11767
Ensembl ID		ENSG00000150433	ENSG00000174417
Uniprot IDs		A2RU14	P34981
PDB IDs
Enriched GO Terms of Interacting Partners?
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